Radiotherapy combined with immunotherapy: the dawn of cancer treatment
Z Zhang, X Liu, D Chen, J Yu - Signal Transduction and Targeted …, 2022 - nature.com
Radiotherapy (RT) is delivered for purposes of local control, but can also exert systemic
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
effect on remote and non-irradiated tumor deposits, which is called abscopal effect. The view …
The crosstalk between tumor cells and the immune microenvironment in breast cancer: implications for immunotherapy
V Salemme, G Centonze, F Cavallo, P Defilippi… - Frontiers in …, 2021 - frontiersin.org
Breast cancer progression is a complex process controlled by genetic and epigenetic factors
that coordinate the crosstalk between tumor cells and the components of tumor …
that coordinate the crosstalk between tumor cells and the components of tumor …
Microneedles for painless transdermal immunotherapeutic applications
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …
the treatment of various diseases. However, owing to the dynamic nature of the immune …
Adaptive mechanisms of tumor therapy resistance driven by tumor microenvironment
Cancer is a disease which frequently has a poor prognosis. Although multiple therapeutic
strategies have been developed for various cancers, including chemotherapy, radiotherapy …
strategies have been developed for various cancers, including chemotherapy, radiotherapy …
Effects of chemotherapy on the immune system: implications for cancer treatment and patient outcomes
A Sharma, S Jasrotia, A Kumar - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
Chemotherapy is a cornerstone of cancer treatment, but it can also induce immune
suppression, which can have significant implications for patient outcomes. This review paper …
suppression, which can have significant implications for patient outcomes. This review paper …
iPSC-derived natural killer cell therapies-expansion and targeting
Treatment of cancer with allogeneic natural killer (NK) cell therapies has seen rapid
development, especially use against hematologic malignancies. Clinical trials of NK cell …
development, especially use against hematologic malignancies. Clinical trials of NK cell …
Polymer micropatches as natural killer cell engagers for tumor therapy
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to
various cancers. Their efficacy, however, is limited by their low persistence and anergy …
various cancers. Their efficacy, however, is limited by their low persistence and anergy …
CAR-NK cells: from natural basis to design for kill
Chimeric antigen receptors (CARs) are fusion proteins with an extracellular antigen
recognition domain and numerous intracellular signaling domains that have been …
recognition domain and numerous intracellular signaling domains that have been …
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Cancer exosomes and natural killer cells dysfunction: biological roles, clinical significance and implications for immunotherapy
R Hosseini, H Sarvnaz, M Arabpour, SM Ramshe… - Molecular cancer, 2022 - Springer
Tumor-derived exosomes (TDEs) play pivotal roles in several aspects of cancer biology. It is
now evident that TDEs also favor tumor growth by negatively affecting anti-tumor immunity …
now evident that TDEs also favor tumor growth by negatively affecting anti-tumor immunity …