Covering: up to mid-2009 The phylum Actinobacteria hosts diverse high G+ C, Gram-
positive bacteria that have evolved a complex chemical language of natural product …

We have developed a general profile for the proteins of the TetR family of repressors. The
stretch that best defines the profile of this family is made up of 47 amino acid residues that …

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork Page 1
REVIEW www.rsc.org/npr | Natural Product Reports Type II polyketide synthases: gaining a …

ABSTRACT A range of gram-negative bacterial species use N-acyl homoserine lactone
(AHL) molecules as quorum-sensing signals to regulate different biological functions …

The red-pigmented prodiginines are bioactive secondary metabolites produced by both
Gram-negative and Gram-positive bacteria. Recently, these tripyrrole molecules have …

There are two basic types of bacterial communication systems—those in which the signal is
directed solely at other organisms and those in which the signal is sensed by the producing …

Small signalling molecules called γ-butyrolactones are mainly produced by Streptomyces
species in which they regulate antibiotic production and morphological differentiation. Their …

Quorum sensing (QS) is a bacterial communication process that depends on the bacterial
population density. It involves small diffusible signaling molecules which activate the …

To compete in nature against other forms of life, microorganisms possess regulatory
mechanisms which control production of their metabolites, thus, protecting against …

Streptomyces bacteria are the major source of antibiotics and other secondary metabolites.
Various environmental and physiological conditions affect the onset and level of production …