Francisella tularensis is the causative agent of the acute disease tularemia. Due to its
extreme infectivity and ability to cause disease upon inhalation, F. tularensis has been …

Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen,
whose virulence requires proliferation inside host cells, including macrophages. Here we …

Francisella tularensis has been recognized as the causative agent of tularaemia for almost a
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …

Francisella tularensis is a Gram-negative intracellular pathogen and the causative agent of
the disease tularemia. Inhalation of as few as 10 bacteria is sufficient to cause severe …

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes
the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host …

Francisella tularensis is a highly infectious bacterium causing the zoonotic disease
tularemia. Its ability to multiply and survive in macrophages is critical for its virulence. By …

The Francisella pathogenicity island (FPI) encodes proteins thought to compose a type VI
secretion system (T6SS) that is required for the intracellular growth of Francisella novicida …

Capsular polysaccharides are important factors in bacterial pathogenesis and have been
the target of a number of successful vaccines. Francisella tularensis has been considered to …

Abstract The bacterium Francisella tularensis (Ft) is a potential weapon of bioterrorism when
aerosolized. Macrophage infection is necessary for disease progression and efficient …