Depression is the most prevalent psychiatric disorder in the world, affecting 4.4% of the
global population. Despite an array of treatment modalities, depressive disorders remain …

Objectives Although several studies have reviewed the suicidal risk of antidepressants, the
conclusions remain inconsistent. We, therefore, performed a meta-analysis of observational …

Objectives. This 2013 update of the practice guidelines for the biological treatment of
unipolar depressive disorders was developed by an international Task Force of the World …

Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …

Objectives Patients in inpatient mental health settings face similar risks (eg, medication
errors) to those in other areas of healthcare. In addition, some unsafe behaviours associated …

Abstract Background This European multicenter study aimed to elucidate suicidality in major
depressive disorder. Previous surveys suggest a prevalence of suicidality in major …

Introduction Due to favorable antidepressant (AD) efficacy and tolerability, selective-
serotonin reuptake inhibitors (SSRIs) are consistently recommended as substances of first …

Emergence of suicidal ideation (TESI) during treatment with antidepressants in major
depression led to a black box warning. We performed a genome-wide association study to …

BACKGROUND: Most predictor analyses search for single predictors or rely on data from
randomized controlled trials. We aimed at detecting a set of clinical baseline variables for …

Background Variation in the course of major depressive disorder (MDD) is not strongly
predicted by existing subtype distinctions. A new subtyping approach is considered here …