Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

MicroRNAs (miRNAs) are naturally occurring, highly conserved families of transcripts (∼ 22
nucleotides in length) that are processed from larger hairpin precursors. miRNAs primarily …

MicroRNAs (miRNAs) are an evolutionarily conserved class of small, regulatory non-coding
RNAs that negatively regulate protein coding gene and other non-coding transcripts …

Summary miR‐155, a microRNA associated with poor prognosis in lymphoma and
leukaemia, has been implicated in the progression of mycosis fungoides (MF), the most …

Gastric cancer is one of the most aggressive malignancies, with limited treatment options in
both locally advanced and metastatic setting, resulting in poor prognosis. Based on genomic …

Alkylating agents constitute a major class of frontline chemotherapeutic drugs that inflict
cytotoxic DNA damage as their main mode of action, in addition to collateral mutagenic …

More than 1.6 million new cases of cancer will be diagnosed in the US in 2016, resulting in
more than 500,000 deaths. Although chemotherapy has been the mainstay of treatment in …

MicroRNA-155 (miR-155) is an oncogenic microRNA that regulates several pathways
involved in cell division and immunoregulation. It is overexpressed in numerous cancers, is …

MicroRNAs (miRNAs) are a class of short non-coding RNA molecules that have attracted
tremendous attention from the biological and biomedical research communities over the …

Epigenetic mechanisms comprising DNA methylation, histone modifications, and noncoding
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …