Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Raman spectroscopy in skeletal tissue disorders and tissue engineering: present and prospective

M Fosca, V Basoli, E Della Bella, F Russo… - … Engineering Part B …, 2022 - liebertpub.com
Musculoskeletal disorders are the most common reason of chronic pain and disability,
representing an enormous socioeconomic burden worldwide. In this review, new biomedical …

[HTML][HTML] Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: a pilot study

SD Gupta, MAJ Finnilä, SS Karhula, S Kauppinen… - Acta Biomaterialia, 2020 - Elsevier
This study investigates the influence of osteoarthritis (OA) disease severity on the bio-
composition of the osteochondral junction at the human tibial plateau using Raman …

Optical investigation of osteoarthritic human cartilage (ICRS grade) by confocal Raman spectroscopy: a pilot study

R Kumar, KM Grønhaug, NK Afseth, V Isaksen… - Analytical and …, 2015 - Springer
Biomolecular changes in the cartilage matrix during the early stage of osteoarthritis may be
detected by Raman spectroscopy. The objective of this investigation was to determine …

Characterization of nano-structural and nano-mechanical properties of osteoarthritic subchondral bone

Q Zuo, S Lu, Z Du, T Friis, J Yao, R Crawford… - BMC musculoskeletal …, 2016 - Springer
Background Although articular cartilage is the primary tissues affected by osteoarthritis (OA),
the underlying subchondral bone also undergoes noticeable changes. Despite the growing …

Optical biomarkers for the diagnosis of osteoarthritis through raman spectroscopy: radiological and biochemical validation using ex vivo human cartilage samples

P Casal-Beiroa, V Balboa-Barreiro, N Oreiro… - Diagnostics, 2021 - mdpi.com
Osteoarthritis (OA) is the most common rheumatic disease, characterized by progressive
articular cartilage degradation. Raman spectroscopy (RS) has been recently proposed as a …

Anti-Candida albicans effect of the protein-carbohydrate fraction obtained from the coelomic fluid of earthworm Dendrobaena veneta

MJ Fiołka, P Czaplewska, K Macur, T Buchwald… - PLoS …, 2019 - journals.plos.org
An antifungal active fraction (AAF) from the coelomic fluid (CF) of the earthworm
Dendrobaena veneta was isolated. The aim of the study was to analyze the antifungal …

Raman microscopic spectroscopy as a diagnostic tool to detect Staphylococcus epidermidis in bone grafts

A Wurm, J Kühn, K Kugel, D Putzer, R Arora… - … Acta Part A: Molecular …, 2022 - Elsevier
Introduction Raman microscopic spectroscopyis a new approach for further characterization
and detection of molecular features in many pathological processes. This technique has …

Raman spectra and ancient life: Vibrational ID profiles of fossilized (bone) tissues

Z Jurašeková, G Fabriciová, LF Silveira… - International Journal of …, 2022 - mdpi.com
Raman micro-spectroscopy is a non-destructive and non-contact analytical technique that
combines microscopy and spectroscopy, thus providing a potential for non-invasive and in …

Comparison of Mid-Infrared Handheld and Benchtop Spectrometers to Detect Staphylococcus epidermidis in Bone Grafts

R Lindtner, A Wurm, K Kugel, J Kühn, D Putzer, R Arora… - Bioengineering, 2023 - mdpi.com
Bone analyses using mid-infrared spectroscopy are gaining popularity, especially with
handheld spectrometers that enable on-site testing as long as the data quality meets …