The actin cytoskeleton and actin-based motility
T Svitkina - Cold Spring Harbor perspectives in biology, 2018 - cshperspectives.cshlp.org
The actin cytoskeleton—a collection of actin filaments with their accessory and regulatory
proteins—is the primary force-generating machinery in the cell. It can produce pushing …
proteins—is the primary force-generating machinery in the cell. It can produce pushing …
Integrin-mediated mechanotransduction
Z Sun, SS Guo, R Fässler - Journal of Cell Biology, 2016 - rupress.org
Cells can detect and react to the biophysical properties of the extracellular environment
through integrin-based adhesion sites and adapt to the extracellular milieu in a process …
through integrin-based adhesion sites and adapt to the extracellular milieu in a process …
A review of cell adhesion studies for biomedical and biological applications
A Ahmad Khalili, MR Ahmad - International journal of molecular sciences, 2015 - mdpi.com
Cell adhesion is essential in cell communication and regulation, and is of fundamental
importance in the development and maintenance of tissues. The mechanical interactions …
importance in the development and maintenance of tissues. The mechanical interactions …
Measuring cell-generated forces: a guide to the available tools
WJ Polacheck, CS Chen - Nature methods, 2016 - nature.com
Forces generated by cells are critical regulators of cell adhesion, signaling, and function,
and they are also essential drivers in the morphogenetic events of development. Over the …
and they are also essential drivers in the morphogenetic events of development. Over the …
Harnessing nanotopography and integrin–matrix interactions to influence stem cell fate
Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …
[HTML][HTML] Focal adhesions, stress fibers and mechanical tension
K Burridge, C Guilluy - Experimental cell research, 2016 - Elsevier
Stress fibers and focal adhesions are complex protein arrays that produce, transmit and
sense mechanical tension. Evidence accumulated over many years led to the conclusion …
sense mechanical tension. Evidence accumulated over many years led to the conclusion …
A layered view on focal adhesions
K Legerstee, AB Houtsmuller - Biology, 2021 - mdpi.com
Simple Summary The cytoskeleton is a network of protein fibres within cells that provide
structure and support intracellular transport. Focal adhesions are protein complexes …
structure and support intracellular transport. Focal adhesions are protein complexes …
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
Metastasis is a complex, multistep process responsible for> 90% of cancer-related deaths. In
addition to genetic and external environmental factors, the physical interactions of cancer …
addition to genetic and external environmental factors, the physical interactions of cancer …
Microtubules in cell migration
C Garcin, A Straube - Essays in biochemistry, 2019 - portlandpress.com
Directed cell migration is critical for embryogenesis and organ development, wound healing
and the immune response. Microtubules are dynamic polymers that control directional …
and the immune response. Microtubules are dynamic polymers that control directional …
Non-muscle myosin II takes centre stage in cell adhesion and migration
M Vicente-Manzanares, X Ma, RS Adelstein… - … reviews Molecular cell …, 2009 - nature.com
Non-muscle myosin II (NM II) is an actin-binding protein that has actin cross-linking and
contractile properties and is regulated by the phosphorylation of its light and heavy chains …
contractile properties and is regulated by the phosphorylation of its light and heavy chains …