An insight into the health-promoting effects of taxifolin (dihydroquercetin)
C Sunil, B Xu - Phytochemistry, 2019 - Elsevier
Abstract Taxifolin (3, 5, 7, 3, 4-pentahydroxy flavanone or dihydroquercetin) is a flavonoid
commonly found in onion, milk thistle, French maritime pine bark and Douglas fir bark. It is …
commonly found in onion, milk thistle, French maritime pine bark and Douglas fir bark. It is …
[HTML][HTML] The hallmarks of flavonoids in cancer
LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …
foods and beverages with known biological activity in cells. From the modulation of …
Redox signaling by reactive electrophiles and oxidants
The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …
Dihydroquercetin supplement alleviates colonic inflammation potentially through improved gut microbiota community in mice
F Wan, H Han, R Zhong, M Wang, S Tang, S Zhang… - Food & Function, 2021 - pubs.rsc.org
The purpose of the current study was to investigate the effect of dietary dihydroquercetin
(DHQ) supplementation on dextran sodium sulfate (DSS)-induced colitis in mice. Mice were …
(DHQ) supplementation on dextran sodium sulfate (DSS)-induced colitis in mice. Mice were …
[HTML][HTML] The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions
A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
[HTML][HTML] Dihydroquercetin attenuates silica-induced pulmonary fibrosis by inhibiting ferroptosis signaling pathway
L Yuan, Y Sun, N Zhou, W Wu, W Zheng… - Frontiers in …, 2022 - frontiersin.org
Silicosis is a fatal occupational lung disease which currently has no effective treatment.
Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-inflammatory, anti …
Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-inflammatory, anti …
Bacterial biosynthesis of flavonoids: Overview, current biotechnology applications, challenges, and prospects
CO Okoye, H Jiang, Y Wu, X Li, L Gao… - Journal of Cellular …, 2023 - Wiley Online Library
Flavonoids are secondary metabolites present in plant organs and tissues. These natural
metabolites are the most prevalent and display a wide range of beneficial physiological …
metabolites are the most prevalent and display a wide range of beneficial physiological …
Targeting the crosstalk between canonical Wnt/β-catenin and inflammatory signaling cascades: A novel strategy for cancer prevention and therapy
Emerging scientific evidence indicates that inflammation is a critical component of tumor
promotion and progression. Most cancers originate from sites of chronic irritation, infections …
promotion and progression. Most cancers originate from sites of chronic irritation, infections …
[HTML][HTML] Epigenetic regulation of NRF2/KEAP1 by phytochemicals
S Bhattacharjee, RH Dashwood - Antioxidants, 2020 - mdpi.com
Epigenetics has provided a new dimension to our understanding of nuclear factor erythroid
2–related factor 2/Kelch-like ECH-associated protein 1 (human NRF2/KEAP1 and murine …
2–related factor 2/Kelch-like ECH-associated protein 1 (human NRF2/KEAP1 and murine …
[HTML][HTML] Polyphenols in colorectal cancer: current state of knowledge including clinical trials and molecular mechanism of action
Polyphenols have been reported to have wide spectrum of biological activities including
major impact on initiation, promotion, and progression of cancer by modulating different …
major impact on initiation, promotion, and progression of cancer by modulating different …