Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
The in vivo fate of polymeric micelles
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …
[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool
One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …
discriminating the carrier-bound signals from the bulk signals of probes. Environment …
One stone two birds: Multifunctional flavonol nanocrystals enable food packaging to both preserve freshness and visually monitor freshness
F Li, T Zhe, K Ma, Y Zhang, R Li, Y Cao, M Li… - Chemical Engineering …, 2023 - Elsevier
Food packaging with both active and intelligent components is critical for reducing food
waste and ensuring food safety. However, concerns about the toxicity of components or …
waste and ensuring food safety. However, concerns about the toxicity of components or …
Biological and intracellular fates of drug nanocrystals through different delivery routes: Recent development enabled by bioimaging and PK modeling
Abstract Nanocrystals have contributed to exciting improvements in the delivery of poorly
water-soluble drugs. The biological and intracellular fates of nanocrystals are currently …
water-soluble drugs. The biological and intracellular fates of nanocrystals are currently …
Drug nanocrystals: Fabrication methods and promising therapeutic applications
IS Mohammad, H Hu, L Yin, W He - International journal of pharmaceutics, 2019 - Elsevier
The drug nanocrystals (NCs) with unique physicochemical properties are now considered
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
as a promising drug delivery system for poorly water-soluble drugs. So far> 20 formulations …
Establishment of In Vitro Dissolution Based on Similarity with In Vivo Dissolution: A Case Study on Aripiprazole
In vitro dissolution that predicts the in vivo performance of solid preparations is extremely
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
important in formulation optimization. Fraction absorbed (F a) has been used to screen in …
Utility of Pickering emulsions in improved oral drug delivery
Highlights•Properties of particle stabilizers are crucial to construct Pickering
emulsions.•Pickering emulsions enhance bioavailability or bioaccessibility of …
emulsions.•Pickering emulsions enhance bioavailability or bioaccessibility of …
[HTML][HTML] Battle of the milky way: Lymphatic targeted drug delivery for pathogen eradication
Many viruses, bacteria, and parasites rely on the lymphatic system for survival, replication,
and dissemination. While conventional anti-infectives can combat infection-causing agents …
and dissemination. While conventional anti-infectives can combat infection-causing agents …