Homocysteine–from disease biomarker to disease prevention
AD Smith, H Refsum - Journal of internal medicine, 2021 - Wiley Online Library
We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …
that are associated with raised concentrations of plasma total homocysteine. The …
[HTML][HTML] Biomarkers of nutrition for development—folate review
Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …
evidence-based advice to anyone with an interest in the role of nutrition in health …
[HTML][HTML] Bioactive phytochemicals in barley
Epidemiological studies have consistently shown that regular consumption of whole grain
barley reduces the risk of developing chronic diseases. The presence of barley fiber …
barley reduces the risk of developing chronic diseases. The presence of barley fiber …
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases
SC Liew, ED Gupta - European journal of medical genetics, 2015 - Elsevier
Abstract The Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is
associated with various diseases (vascular, cancers, neurology, diabetes, psoriasis, etc) …
associated with various diseases (vascular, cancers, neurology, diabetes, psoriasis, etc) …
Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues
We respond to criticisms of Mendelian randomization (MR) by Mukamal, Stampfer and Rimm
(MSR). MSR consider that MR is receiving too much attention and should be renamed. We …
(MSR). MSR consider that MR is receiving too much attention and should be renamed. We …
Homocysteine, B vitamins, and cardiovascular disease: a Mendelian randomization study
Background Whether a modestly elevated homocysteine level is causally associated with an
increased risk of cardiovascular disease remains unestablished. We conducted a Mendelian …
increased risk of cardiovascular disease remains unestablished. We conducted a Mendelian …
Hyperhomocysteinemia as a risk factor and potential nutraceutical target for certain pathologies
C Tinelli, A Di Pino, E Ficulle, S Marcelli… - Frontiers in …, 2019 - frontiersin.org
Hyperhomocysteinemia is recognized as a risk factor for several diseases, including
cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite …
cardiovascular and neurological conditions. Homocysteine (HCys) is a key metabolite …
Mendelian randomization studies: a review of the approaches used and the quality of reporting
AGC Boef, OM Dekkers… - International journal of …, 2015 - academic.oup.com
Background: Mendelian randomization (MR) studies investigate the effect of genetic
variation in levels of an exposure on an outcome, thereby using genetic variation as an …
variation in levels of an exposure on an outcome, thereby using genetic variation as an …
Potential of garlic (Allium sativum) in lowering high blood pressure: mechanisms of action and clinical relevance
K Ried, P Fakler - Integrated blood pressure control, 2014 - Taylor & Francis
Garlic supplements have shown promise in the treatment of uncontrolled hypertension,
lowering blood pressure (BP) by about 10 mmHg systolic and 8 mmHg diastolic, similar to …
lowering blood pressure (BP) by about 10 mmHg systolic and 8 mmHg diastolic, similar to …
[HTML][HTML] Effects of homocysteine lowering with B vitamins on cognitive aging: meta-analysis of 11 trials with cognitive data on 22,000 individuals
R Clarke, D Bennett, S Parish, S Lewington… - The American journal of …, 2014 - Elsevier
Background: Elevated plasma homocysteine is a risk factor for Alzheimer disease, but the
relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain …
relevance of homocysteine lowering to slow the rate of cognitive aging is uncertain …