Quality-controlled R-loop meta-analysis reveals the characteristics of R-loop consensus regions
R-loops are three-stranded nucleic acid structures formed from the hybridization of RNA and
DNA. While the pathological consequences of R-loops have been well-studied to date, the …
DNA. While the pathological consequences of R-loops have been well-studied to date, the …
[HTML][HTML] Enhancer RNA expression in response to glucocorticoid treatment in murine macrophages
F Greulich, KA Bielefeld, R Scheundel, A Mechtidou… - Cells, 2021 - mdpi.com
Glucocorticoids are potent anti-inflammatory drugs; however, their molecular mode of action
remains complex and elusive. They bind to the glucocorticoid receptor (GR), a nuclear …
remains complex and elusive. They bind to the glucocorticoid receptor (GR), a nuclear …
Kinetic networks identify TWIST2 as a key regulatory node in adipogenesis
AB Dutta, DS Lank, RK Przanowska… - Genome …, 2023 - genome.cshlp.org
Adipocytes contribute to metabolic disorders such as obesity, diabetes, and atherosclerosis.
Prior characterizations of the transcriptional network driving adipogenesis have overlooked …
Prior characterizations of the transcriptional network driving adipogenesis have overlooked …
[HTML][HTML] Alternative splicing is coupled to gene expression in a subset of variably expressed genes
G Karlebach, R Steinhaus, D Danis, M Devoucoux… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Numerous factors regulate alternative splicing of human genes at a co-transcriptional level.
However, how alternative splicing depends on the regulation of gene expression is poorly …
However, how alternative splicing depends on the regulation of gene expression is poorly …