Less is more: Antibiotics at the beginning of life
M Stocker, C Klingenberg, L Navér, V Nordberg… - Nature …, 2023 - nature.com
Antibiotic exposure at the beginning of life can lead to increased antimicrobial resistance
and perturbations of the developing microbiome. Early-life microbiome disruption increases …
and perturbations of the developing microbiome. Early-life microbiome disruption increases …
The impact of human milk on necrotizing enterocolitis: a systematic review and meta-analysis
E Altobelli, PM Angeletti, A Verrotti, R Petrocelli - Nutrients, 2020 - mdpi.com
Background. Premature infants receiving breastfeed have a lower incidence of NEC than
those fed preterm formula. This study aimed:(1) to update a systematic review and meta …
those fed preterm formula. This study aimed:(1) to update a systematic review and meta …
Necrotizing enterocolitis, gut microbes, and sepsis
Necrotizing enterocolitis (NEC) is a devastating disease in premature infants and the
leading cause of death and disability from gastrointestinal disease in this vulnerable …
leading cause of death and disability from gastrointestinal disease in this vulnerable …
Necrotizing enterocolitis: the role of hypoxia, gut microbiome, and microbial metabolites
A Kaplina, S Kononova, E Zaikova, T Pervunina… - International Journal of …, 2023 - mdpi.com
Necrotizing enterocolitis (NEC) is a life-threatening disease that predominantly affects very
low birth weight preterm infants. Development of NEC in preterm infants is accompanied by …
low birth weight preterm infants. Development of NEC in preterm infants is accompanied by …
Risk factors for late-onset sepsis in preterm infants: a multicenter case-control study
S El Manouni El Hassani, DJC Berkhout, HJ Niemarkt… - Neonatology, 2019 - karger.com
Background: Late-onset sepsis (LOS) in preterm infants is a leading cause of mortality and
morbidity. Timely recognition and initiation of antibiotics are important factors for improved …
morbidity. Timely recognition and initiation of antibiotics are important factors for improved …
The metabolome and the gut microbiota for the prediction of necrotizing enterocolitis and spontaneous intestinal perforation: a systematic review
L Moschino, G Verlato, M Duci, ME Cavicchiolo… - Nutrients, 2022 - mdpi.com
Necrotizing enterocolitis (NEC) is the most devastating gastrointestinal emergency in
preterm neonates. Research on early predictive biomarkers is fundamental. This is a …
preterm neonates. Research on early predictive biomarkers is fundamental. This is a …
[HTML][HTML] Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: a population-based cohort
A Vatne, N Hapnes, HJ Stensvold, I Dalen… - The Journal of …, 2023 - Elsevier
Objective The objective of this study was to evaluate the association between empirical
antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the …
antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the …
Association between duration of early empiric antibiotics and necrotizing enterocolitis and late-onset sepsis in preterm infants: a multicenter cohort study
TH Dierikx, N Deianova, J Groen, DC Vijlbrief… - European journal of …, 2022 - Springer
The threshold to initiate empiric antibiotics for suspicion of early-onset sepsis (EOS) is low in
preterm infants. Antibiotics' effects on short-term outcomes have recently been debated. We …
preterm infants. Antibiotics' effects on short-term outcomes have recently been debated. We …
Infection prevention for extremely low birth weight infants in the NICU
N Fleiss, S Tarun, RA Polin - Seminars in Fetal and Neonatal Medicine, 2022 - Elsevier
Extremely preterm infants are particularly vulnerable to systemic infections secondary to
their immature immune defenses, prolonged hospitalizations, delays in enteral feeding …
their immature immune defenses, prolonged hospitalizations, delays in enteral feeding …
Timing of milk expression following delivery in mothers delivering preterm very low birth weight infants: a randomized trial
LA Parker, S Sullivan, C Kruger, M Mueller - Journal of Perinatology, 2020 - nature.com
Objective To determine the effect of timing of expression initiation on mother's own milk
production and time to secretory activation in mothers of preterm infants. Study design 180 …
production and time to secretory activation in mothers of preterm infants. Study design 180 …