Combining endometrial assembloids and blastoids to delineate the molecular roadmap of implantation
Y Cai, N Li, H Li - Stem Cell Reviews and Reports, 2023 - Springer
Implantation is the process by which a competent blastocyst burrows into the receptive
uterus to support embryo development. Successful implantation is of the utmost importance …
uterus to support embryo development. Successful implantation is of the utmost importance …
Current understanding of the pathogenesis of placenta accreta spectrum disorder with focus on mitochondrial function
H Kobayashi, S Matsubara, C Yoshimoto… - Journal of Obstetrics …, 2024 - Wiley Online Library
Aim The refinement of assisted reproductive technology, including the development of
cryopreservation techniques (vitrification) and ovarian stimulation protocols, makes frozen …
cryopreservation techniques (vitrification) and ovarian stimulation protocols, makes frozen …
Lhx2 in germ cells suppresses endothelial cell migration in the developing ovary
LIM-homeobox genes play multiple roles in developmental processes, but their roles in
gonad development are not completely understood. Herein, we report that Lhx2, Ils2 …
gonad development are not completely understood. Herein, we report that Lhx2, Ils2 …
Steroid receptor coactivator‐2 drives epithelial reprogramming that enables murine embryo implantation
VK Maurya, MM Szwarc, DM Lonard… - The FASEB …, 2023 - Wiley Online Library
Although we have shown that steroid receptor coactivator‐2 (SRC‐2), a member of the
p160/SRC family of transcriptional coregulators, is essential for decidualization of both …
p160/SRC family of transcriptional coregulators, is essential for decidualization of both …
[HTML][HTML] Marine Staurosporine Analogues: Activity and Target Identification in Triple-Negative Breast Cancer
RY Chen, LJ Ding, YJ Liu, JJ Shi, J Yu, CY Li, JF Lu… - Marine Drugs, 2024 - mdpi.com
Triple-negative breast cancer (TNBC) is a subtype of breast cancer with high mortality and
drug resistance and no targeted drug available at present. Compound 4, a staurosporine …
drug resistance and no targeted drug available at present. Compound 4, a staurosporine …
The G-protein-coupled estrogen receptor, a gene co-expressed with ERα in breast tumors, is regulated by estrogen-ERα signalling in ERα positive breast cancer cells
GPER is a seven transmembrane G-protein-coupled estrogen receptor that mediates rapid
estrogen actions. Large volumes of data have revealed its association with …
estrogen actions. Large volumes of data have revealed its association with …
The lncRNA LINC00339-encoded peptide promotes trophoblast adhesion to endometrial cells via MAPK and PI3K-Akt signaling pathways
B Zhou, G Yu, M Zhao, Y Li, J Li, Y Xiang… - Journal of Assisted …, 2024 - Springer
Background Endometrial receptivity (ER), a pivotal event for successful embryo implantation,
refers to the capacity of endometrium to allow the adhesion of the trophectoderm of the …
refers to the capacity of endometrium to allow the adhesion of the trophectoderm of the …
[HTML][HTML] Endometrial E-cadherin and N-cadherin Expression during the Mid-Secretory Phase of Women with Ovarian Endometrioma or Uterine Fibroids
BS Yun, NY Yun, JE Lee, M Go, HY Jang… - Journal of Personalized …, 2024 - mdpi.com
Background: Endometriosis and uterine fibroids are benign conditions frequently linked to
subfertility/infertility. Recent research has highlighted the importance of epithelial …
subfertility/infertility. Recent research has highlighted the importance of epithelial …
LHX2 in germ cells control tubular organization in the developing mouse testis
In the gonads of mammalian XY embryos, the organization of cords is the hallmark of testis
development. This organization is thought to be controlled by interactions of the Sertoli cells …
development. This organization is thought to be controlled by interactions of the Sertoli cells …
[HTML][HTML] Estradiol-Induced Epithelial to Mesenchymal Transition and Migration Are Inhibited by Blocking c-Src Kinase in Breast Cancer Cell Lines
JE Jiménez-Salazar, RM Rivera-Escobar… - Journal of Breast …, 2023 - ncbi.nlm.nih.gov
Purpose The epithelial-to-mesenchymal transition (EMT) is the main event that favors cell
migration and metastasis in breast cancer. Previously, we demonstrated that 1 nM estradiol …
migration and metastasis in breast cancer. Previously, we demonstrated that 1 nM estradiol …