[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022 - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

Pharmacologically active phytomolecules isolated from traditional antidiabetic plants and their therapeutic role for the management of diabetes mellitus

P Ansari, S Akther, JMA Hannan, V Seidel, NJ Nujat… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a chronic complication that affects people of all ages. The increased
prevalence of diabetes worldwide has led to the development of several synthetic drugs to …

[HTML][HTML] Plants secondary metabolites as blood glucose-lowering molecules

MB Shehadeh, GARY Suaifan, AM Abu-Odeh - Molecules, 2021 - mdpi.com
Recently, significant advances in modern medicine and therapeutic agents have been
achieved. However, the search for effective antidiabetic drugs is continuous and …

Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats

F Altındağ, MÇ Rağbetli, U Özdek, N Koyun… - Food and Chemical …, 2021 - Elsevier
In the present study, we aimed to investigate the effect of individual and combined treatment
of sinapic acid (SA) and ellagic acid (EA) in streptozotocin (STZ)-induced diabetic rats. Rats …

Piperine ameliorates ischemic stroke-induced brain injury in rats by regulating the PI3K/AKT/mTOR pathway

Y Zhang, M Yang, Q Yuan, Q He, H Ping, J Yang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Piperine (PIP), a main active component isolated from
Piper nigrum L., exerts neuroprotective effects in a rat model of ischemic stroke (IS) …

[HTML][HTML] Ellagic acid regulates hyperglycemic state through modulation of pancreatic IL-6 and TNF-α immunoexpression

MM Elbandrawy, O Sweef, D Elgamal… - Saudi Journal of …, 2022 - Elsevier
Abstract Background Type 2 diabetes (T2DM) is a chronic metabolic disorder. Although
therapeutic pharmaceutical agents continue to advance, herbal medicines are potential …

Ellagic acid: Insight into its protective effects in age-associated disorders

Deepika, PK Maurya - 3 Biotech, 2022 - Springer
The disparity in the free radical generation and the production of antioxidants to counteract
its effect is known as oxidative stress. Oxidative stress causes damage to the …

Preventive effect of ellagic acid on cardiac dysfunction in diabetic mice through regulating DNA hydroxymethylation

S Pei, H Zhao, L Chen, X He, Q Hua… - Journal of Agricultural …, 2022 - ACS Publications
Ellagic acid (EA) improves mitochondrial dysfunction and protects diabetic hearts. The
mitochondrial tricarboxylic acid (TCA) cycle regulates DNA 5-hydroxymethylcytosine (5hmC) …

Ellagic acid as potential therapeutic compound for diabetes and its complications: a systematic review from bench to bed

H Ghazaee, A Raouf Sheibani, H Mahdian… - Naunyn-Schmiedeberg's …, 2024 - Springer
Diabetes mellitus (DM) is a worldwide-concerning disease with a rising prevalence. There
are many ongoing studies aimed at finding new and effective treatments. Ellagic acid (EA) is …

Evaluation of phytochemical profile, and antioxidant, antidiabetic activities of indigenous Thai fruits

J Prakulanon, S Duangsrisai, S Vajrodaya… - PeerJ, 2024 - peerj.com
Background This research aims to explore the phenolics identification, phenolics
quantification, antioxidant and potential biofunctional properties of lesser-known Thai fruits …