Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-
dependent, lipid peroxidation-driven membrane destruction that can be inhibited by …

Cellular quality control systems sense and mediate homeostatic responses to prevent the
buildup of aberrant macromolecules, which arise from errors during biosynthesis, damage …

The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …

Endothelial dysfunction contributes to cardiovascular diseases, including hypertension,
atherosclerosis, and coronary artery disease, which are also characterized by insulin …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Numerous epidemiologic time-series studies have shown generally consistent associations
of cardiovascular hospital admissions and mortality with outdoor air pollution, particularly …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

Nitrogen dioxide and carbonate radical anion have received sporadic attention thus far from
biological investigators. However, accumulating data on the biochemical reactions of nitric …

We review gases that can affect oxidative stress and that themselves may be radicals. We
discuss O2 toxicity, invoking superoxide, hydrogen peroxide, and the hydroxyl radical. We …

The process of lipid peroxidation is widespread in biology and is mediated through both
enzymatic and non-enzymatic pathways. A significant proportion of the oxidized lipid …