Smart biosensors for cancer diagnosis based on graphene quantum dots

D Iannazzo, C Espro, C Celesti, A Ferlazzo, G Neri - Cancers, 2021 - mdpi.com
Simple Summary Graphene quantum dots, the next generation of graphene family, due to
their remarkable physical and chemical properties, have been shown to be ideal sensing …

[HTML][HTML] Recent advances in the development of sialyltransferase inhibitors to control cancer metastasis: A comprehensive review

R Al Saoud, A Hamrouni, A Idris, WK Mousa… - Biomedicine & …, 2023 - Elsevier
Metastasis accounts for the majority of cancer-associated mortalities, representing a huge
health and economic burden. One of the mechanisms that enables metastasis is …

Highly-sensitive label-free deep profiling of N-glycans released from biomedically-relevant samples

AL Marie, S Ray, AR Ivanov - Nature Communications, 2023 - nature.com
Alterations of protein glycosylation can serve as sensitive and specific disease biomarkers.
Labeling procedures for improved separation and detectability of oligosaccharides have …

Selectins—the two Dr. Jekyll and Mr. Hyde faces of adhesion molecules—a review

I Tvaroška, C Selvaraj, J Koča - Molecules, 2020 - mdpi.com
Selectins belong to a group of adhesion molecules that fulfill an essential role in immune
and inflammatory responses and tissue healing. Selectins are glycoproteins that decode the …

Polypeptide GalNAc-Ts: from redundancy to specificity

M de Las Rivas, E Lira-Navarrete, TA Gerken… - Current opinion in …, 2019 - Elsevier
Mucin-type O-glycosylation is a post-translational modification (PTM) that is predicted to
occur in more than the 80% of the proteins that pass through the Golgi apparatus. This PTM …

Early detection of tumour-associated antigens: Assessment of point-of-care electrochemical immunoassays

M Puiu, C Nativi, C Bala - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The development of highly sensitive and selective platforms for cancer biomarkers detection
plays a crucial for early diagnosis, monitoring disease progression, and subsequent cancer …

Plant lectins and their usage in preparing targeted nanovaccines for cancer immunotherapy

B Gupta, D Sadaria, VU Warrier, A Kirtonia… - Seminars in Cancer …, 2022 - Elsevier
Plant lectins, a natural source of glycans with a therapeutic potential may lead to the
discovery of new targeted therapies. Glycans extracted from plant lectins are known to act as …

Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV

LB Giron, CS Palmer, Q Liu, X Yin… - Nature …, 2021 - nature.com
Non-invasive biomarkers that predict HIV remission after antiretroviral therapy (ART)
interruption are urgently needed. Such biomarkers can improve the safety of analytic …

Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

PF Zhang, ZY Wu, WB Zhang, YQ He, K Chen… - Nature …, 2023 - nature.com
Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …

High-sensitivity glycan profiling of blood-derived immunoglobulin G, plasma, and extracellular vesicle isolates with capillary zone electrophoresis-mass spectrometry

AL Marie, S Ray, S Lu, J Jones, I Ghiran… - Analytical …, 2021 - ACS Publications
We developed a highly sensitive method for profiling of N-glycans released from proteins
based on capillary zone electrophoresis coupled to electrospray ionization mass …