Introduction Major organ-based in vitro diagnostic (IVD) tests like ALT/AST for the liver and
cardiac troponins for the heart are established, but an approved IVD blood test for the brain …

Introduction Diffuse axonal injury (DAI), with high mortality and morbidity both in children
and adults, is one of the most severe pathological consequences of traumatic brain injury …

Objective We used the lateral fluid percussion injury (LFPI) model of moderate‐to‐severe
traumatic brain injury (TBI) to identify early plasma biomarkers predicting injury, early post …

Purpose We analysed the impact of early systemic insults (hypoxemia and hypotension, SIs)
on brain injury biomarker profiles, acute care requirements during intensive care unit (ICU) …

Background Traumatic brain injury (TBI) triggers autonomic dysfunction and inflammatory
response that can result in secondary brain injuries. Dexmedetomidine is an alpha-2 agonist …

Brain injury is a multifaceted condition arising from nonspecific damage to nervous tissue.
The resulting cognitive developmental impairments reverberate through patients' lives …

Acute brain injuries, such as traumatic brain injury and ischemic and hemorragic stroke, are
a leading cause of death and disability worldwide. While characterized by clearly distict …