Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - Am Heart Assoc
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

RF Keep, Y Hua, G Xi - The Lancet Neurology, 2012 - thelancet.com
Intracerebral haemorrhage accounts for about 10–15% of all strokes and is associated with
high mortality and morbidity. No successful phase 3 clinical trials for this disorder have been …

Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American …

JC Hemphill III, SM Greenberg, CS Anderson, K Becker… - Stroke, 2015 - Am Heart Assoc
Purpose—The aim of this guideline is to present current and comprehensive
recommendations for the diagnosis and treatment of spontaneous intracerebral …

Immune interventions in stroke

Y Fu, Q Liu, J Anrather, FD Shi - Nature Reviews Neurology, 2015 - nature.com
Approaches for the effective management of acute stroke are sparse, and many measures
for brain protection fail. However, our ability to modulate the immune system and modify the …

Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American …

LB Morgenstern, JC Hemphill III, C Anderson, K Becker… - Stroke, 2010 - Am Heart Assoc
Purpose—The aim of this guideline is to present current and comprehensive
recommendations for the diagnosis and treatment of acute spontaneous intracerebral …

Intracerebral haemorrhage

AI Qureshi, AD Mendelow, DF Hanley - The Lancet, 2009 - thelancet.com
Intracerebral haemorrhage is an important public health problem leading to high rates of
death and disability in adults. Although the number of hospital admissions for intracerebral …

Injury mechanisms in acute intracerebral hemorrhage

DA Wilkinson, AS Pandey, BG Thompson, RF Keep… - …, 2018 - Elsevier
Intracerebral hemorrhage (ICH) is the most common hemorrhagic stroke subtype, and rates
are increasing with an aging population. Despite an increase in research and trials of …

[HTML][HTML] Neuroinflammation after intracerebral hemorrhage

E Mracsko, R Veltkamp - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Spontaneous intracerebral hemorrhage (ICH) is a particularly severe type of stroke for which
no specific treatment has been established yet. Although preclinical models of ICH have …

Mechanisms of brain injury after intracerebral haemorrhage

G Xi, RF Keep, JT Hoff - The Lancet Neurology, 2006 - thelancet.com
The past decade has resulted in a rapid increase in knowledge of mechanisms underlying
brain injury induced by intracerebral haemorrhage (ICH). Animal studies have suggested …

Ischemia-reperfusion injury in stroke

M Nour, F Scalzo, DS Liebeskind - Interventional neurology, 2013 - karger.com
Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic
stroke continue to debilitate patients with devastating outcomes at both the personal and …