Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Succinate dehydrogenase (SDH) is one of the enzymes of the tricarboxylic acid cycle (Krebs
cycle) and complex II of the mitochondrial respiratory chain. A class of fungicides (SDHIs) …

Free radicals play a vital role in all kinds of biological processes including immune
responses. However, free radicals have short lifetimes and are highly reactive, making them …

The sulfoximine insecticide sulfoxaflor is regarded as a potential substitute for
neonicotinoids that were recently banned in the EU due to their side effects on bees. Like …

Fluxapyroxad (Flu), one of the succinate dehydrogenase-inhibited (SDHI) fungicides, has
been extensively used in crop fungal disease control. Despite its increasing use in modern …

Succinate dehydrogenase inhibitor (SDHI) fungicides are increasingly used in agriculture to
combat molds and fungi, two major threats to both food supply and public health. However …

In France, more than 90% of monitored watercourses are contaminated with pesticides. This
high contamination level increases at the head of agricultural watersheds, where dilution …

Research focused on succinate dehydrogenase (SDH) and its substrate, succinate,
culminated in the 1950s accompanying the rapid development of research dedicated to …

Succinate dehydrogenase inhibitors (SDHi) are fungicides used to control the proliferation of
pathogenic fungi in crops. Their mode of action is based on blocking the activity of succinate …

There is increasing evidence that links mitochondrial off-target effects with organ toxicities.
For this reason, predictive strategies need to be developed to identify mitochondrial …