Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …

There have been extensive developments on cellular and molecular mechanisms of
immune regulation in allergy, asthma, autoimmune diseases, tumor development, organ …

Rationale: Allergic inflammation has been linked to increased susceptibility to viral illnesses,
but it is unclear whether this association is causal. Objectives: To test whether omalizumab …

Asthma and chronic obstructive pulmonary disease (COPD) are major causes of global
morbidity and mortality worldwide. The clinical course of both asthma and COPD are …

Asthma is a chronic inflammatory airway disease characterized by variable airflow
obstruction in response to a wide range of exogenous stimuli. The airway epithelium is the …

Respiratory viral infections, particularly those caused by rhinovirus, exacerbate chronic
respiratory inflammatory diseases, such as asthma and chronic obstructive pulmonary …

The hallmark pathological features of asthma include airway eosinophilic inflammation and
structural changes (remodelling) which are associated with an irreversible loss in lung …

The ongoing SARS-CoV-2 pandemic continues to lead to high morbidity and mortality.
During pregnancy, severe maternal and neonatal outcomes and placental pathological …

The interferon (IFN) induced anti-viral response is amongst the earliest and most potent of
the innate responses to fight viral infection. The induction of the Janus kinase/signal …

The bronchial epithelium is continuously exposed to a multitude of noxious challenges in
inhaled air. Cellular contact with most damaging agents is reduced by the action of the …