Aptamers chemistry: Chemical modifications and conjugation strategies

F Odeh, H Nsairat, W Alshaer, MA Ismail, E Esawi… - Molecules, 2019 - mdpi.com
Soon after they were first described in 1990, aptamers were largely recognized as a new
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …

Smart nanocarriers as an emerging platform for cancer therapy: A review

M Kenchegowda, M Rahamathulla, U Hani, MY Begum… - Molecules, 2021 - mdpi.com
Cancer is a group of disorders characterized by uncontrolled cell growth that affects around
11 million people each year globally. Nanocarrier-based systems are extensively used in …

Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy

Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Gold nanoparticles enlighten the future of cancer theranostics

J Guo, K Rahme, Y He, LL Li, JD Holmes… - International journal …, 2017 - Taylor & Francis
Development of multifunctional nanomaterials, one of the most interesting and advanced
research areas in the field of nanotechnology, is anticipated to revolutionize cancer …

[HTML][HTML] Aptamers used for biosensors and targeted therapy

Y Ning, J Hu, F Lu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Aptamers are single-stranded nucleic acid sequences that can bind to target molecules with
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …

Development of “smart” drug delivery systems for chemo/PDT synergistic treatment

M Yu, R Cao, Z Ma, M Zhu - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Although chemotherapy and photodynamic therapy (PDT) have been developed for fighting
cancer, the complex and heterogeneous nature of tumors makes it difficult for a single …

Aptamer-guided nanomedicines for anticancer drug delivery

W Alshaer, H Hillaireau, E Fattal - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …

Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer

M Razlansari, S Jafarinejad, A Rahdar… - Molecular and Cellular …, 2023 - Springer
Today, RNA aptamers are being considered promising theranostic tools against a wide
variety of disorders. RNA aptamers can fold into complex shapes and bind to diverse …

Surface chemistry of gold nanoparticles for bacterial detection and antimicrobial applications

P Ge, J Zhang, T Ding, Y Xianyu - ACS Materials Letters, 2023 - ACS Publications
Bacteria can infect the human body and cause disease, which endangers public safety. The
emergence of multidrug-resistant bacteria poses a great challenge on the treatment of …

[HTML][HTML] Recent advances of light-mediated theranostics

X Ai, J Mu, B Xing - Theranostics, 2016 - ncbi.nlm.nih.gov
Currently, precision theranostics have been extensively demanded for the effective
treatment of various human diseases. Currently, efficient therapy at the targeted disease …