Aptamers chemistry: Chemical modifications and conjugation strategies
Soon after they were first described in 1990, aptamers were largely recognized as a new
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …
class of biological ligands that can rival antibodies in various analytical, diagnostic, and …
Smart nanocarriers as an emerging platform for cancer therapy: A review
M Kenchegowda, M Rahamathulla, U Hani, MY Begum… - Molecules, 2021 - mdpi.com
Cancer is a group of disorders characterized by uncontrolled cell growth that affects around
11 million people each year globally. Nanocarrier-based systems are extensively used in …
11 million people each year globally. Nanocarrier-based systems are extensively used in …
Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy
Z Fu, J Xiang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
Gold nanoparticles enlighten the future of cancer theranostics
Development of multifunctional nanomaterials, one of the most interesting and advanced
research areas in the field of nanotechnology, is anticipated to revolutionize cancer …
research areas in the field of nanotechnology, is anticipated to revolutionize cancer …
[HTML][HTML] Aptamers used for biosensors and targeted therapy
Y Ning, J Hu, F Lu - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Aptamers are single-stranded nucleic acid sequences that can bind to target molecules with
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …
high selectivity and affinity. Most aptamers are screened in vitro by a combinatorial biology …
Development of “smart” drug delivery systems for chemo/PDT synergistic treatment
M Yu, R Cao, Z Ma, M Zhu - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Although chemotherapy and photodynamic therapy (PDT) have been developed for fighting
cancer, the complex and heterogeneous nature of tumors makes it difficult for a single …
cancer, the complex and heterogeneous nature of tumors makes it difficult for a single …
Aptamer-guided nanomedicines for anticancer drug delivery
Aptamers are versatile nucleic acid-based macromolecules characterized by their high
affinity and specificity to a specific target. Taking advantage of such binding properties …
affinity and specificity to a specific target. Taking advantage of such binding properties …
Development and classification of RNA aptamers for therapeutic purposes: an updated review with emphasis on cancer
M Razlansari, S Jafarinejad, A Rahdar… - Molecular and Cellular …, 2023 - Springer
Today, RNA aptamers are being considered promising theranostic tools against a wide
variety of disorders. RNA aptamers can fold into complex shapes and bind to diverse …
variety of disorders. RNA aptamers can fold into complex shapes and bind to diverse …
Surface chemistry of gold nanoparticles for bacterial detection and antimicrobial applications
Bacteria can infect the human body and cause disease, which endangers public safety. The
emergence of multidrug-resistant bacteria poses a great challenge on the treatment of …
emergence of multidrug-resistant bacteria poses a great challenge on the treatment of …
[HTML][HTML] Recent advances of light-mediated theranostics
Currently, precision theranostics have been extensively demanded for the effective
treatment of various human diseases. Currently, efficient therapy at the targeted disease …
treatment of various human diseases. Currently, efficient therapy at the targeted disease …