A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults

DER Warburton, S Charlesworth, A Ivey… - International journal of …, 2010 - Springer
This systematic review examines critically the scientific basis for Canada's Physical Activity
Guide for Healthy Active Living for adults. Particular reference is given to the dose-response …

[HTML][HTML] The role of ALDH2 in tumorigenesis and tumor progression: Targeting ALDH2 as a potential cancer treatment

H Zhang, L Fu - Acta Pharmaceutica Sinica B, 2021 - Elsevier
A major mitochondrial enzyme for protecting cells from acetaldehyde toxicity is aldehyde
dehydrogenase 2 (ALDH2). The correlation between ALDH2 dysfunction and …

Aldehyde dehydrogenase 2 as a therapeutic target in oxidative stress-related diseases: post-translational modifications deserve more attention

J Gao, Y Hao, X Piao, X Gu - International journal of molecular sciences, 2022 - mdpi.com
Aldehyde dehydrogenase 2 (ALDH2) has both dehydrogenase and esterase activity; its
dehydrogenase activity is closely related to the metabolism of aldehydes produced under …

Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues

SA Marchitti, DJ Orlicky, C Brocker… - … of Histochemistry & …, 2010 - journals.sagepub.com
Aldehyde dehydrogenase (ALDH) enzymes are critical in the detoxification of endogenous
and exogenous aldehydes. Our previous findings indicate that the ALDH3B1 enzyme is …

CYP2E1 and risk of chemically mediated cancers

DT Trafalis, ES Panteli, A Grivas, C Tsigris… - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: Among various human CYPs, CYP2E1 is of particular interest
because of its involvement in the metabolic activation of many low molecular mass …

[PDF][PDF] Alcohol Consumption, Aldehyde Dehydrogenase 2 Gene Polymorphisms, and Cardiovascular Health in Korea

MJ Shin, Y Cho, G Davey Smith - Yonsei medical journal, 2017 - synapse.koreamed.org
Alcohol consumption is a serious health issue in Korea in terms of the amount consumed
and the behavior related to its consumption. Aldehyde dehydrogenase 2 (ALDH2) is a key …

Contributing roles of CYP2E1 and other cytochrome P450 isoforms in alcohol-related tissue injury and carcinogenesis

BJ Song, MA Abdelmegeed, YE Cho, M Akbar… - … : Advances in Cell …, 2019 - Springer
The purpose of this review is to briefly summarize the roles of alcohol (ethanol) and related
compounds in promoting cancer and inflammatory injury in many tissues. Long-term chronic …

Identification of informative genes and pathways using an improved penalized support vector machine with a weighting scheme

WH Chan, MS Mohamad, S Deris, N Zaki… - Computers in biology …, 2016 - Elsevier
Incorporation of pathway knowledge into microarray analysis has brought better biological
interpretation of the analysis outcome. However, most pathway data are manually curated …

Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis

Y Wang, H Yang, L Li, H Wang, C Zhang, G Yin… - European Journal of …, 2010 - Elsevier
Genetic variations in metabolic genes are thought to modify the metabolic process of
carcinogens and are suggested to be related to cancer risk. However, epidemiological …

Effect of ALDH2 polymorphism on cancer risk in Asians: A meta-analysis

W Zuo, Z Zhan, L Ma, W Bai, S Zeng - Medicine, 2019 - journals.lww.com
Effect of ALDH2 polymorphism on cancer risk in Asians: A met... : Medicine Effect of ALDH2
polymorphism on cancer risk in Asians: A meta-analysis : Medicine Log in or Register Get new …