Spatial topology of organelle is a new breast cancer cell classifier

L Wang, J Goldwag, M Bouyea, J Barra, K Matteson… - Iscience, 2023 - cell.com
Genomics and proteomics have been central to identify tumor cell populations, but more
accurate approaches to classify cell subtypes are still lacking. We propose a new …

Performant web-based interactive visualization tool for spatially-resolved transcriptomics experiments

C Sriworarat, A Nguyen, NJ Eagles… - Biological …, 2023 - cambridge.org
High-resolution and multiplexed imaging techniques are giving us an increasingly detailed
observation of a biological system. However, sharing, exploring, and customizing the …

Live Cell Painting: image-based profiling in live cells using Acridine Orange

F Garcia-Fossa, T Moraes-Lacerda… - bioRxiv, 2024 - biorxiv.org
Image-based profiling has been used to analyze cell health, drug mechanism of action,
CRISPR-edited cells, and overall cytotoxicity. Cell Painting is a broadly used image-based …

Cross-modality profiling of high-content microscopy images with deep learning

J Cross-Zamirski - 2023 - repository.cam.ac.uk
In this thesis we investigate the use of deep learning for cross-modality and multi-modal
image-based profiling applications. In particular, we explore the utility of the brightfield …