ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

[HTML][HTML] Molecular machinery and interplay of apoptosis and autophagy in coronary heart disease

Y Dong, H Chen, J Gao, Y Liu, J Li, J Wang - Journal of molecular and …, 2019 - Elsevier
Coronary heart disease (CHD) is a common heart disease and the leading cause of
cardiovascular death. Apoptosis and autophagy are two forms of programmed cell deaths …

Potential and therapeutic roles of diosmin in human diseases

E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …

Assessment of anticancer, antimicrobial, antidiabetic, anti-obesity and antioxidant activity of Ocimum Basilicum seeds essential oil from Palestine

AM Eid, N Jaradat, N Shraim, M Hawash, L Issa… - … Medicine and Therapies, 2023 - Springer
Background Many modern pharmaceutical researchers continue to focus on the discovery
and evaluation of natural compounds for possible therapies for obesity, diabetes, infections …

[HTML][HTML] Melanin: A promising source of functional food ingredient

X Yang, C Tang, Q Zhao, Y Jia, Y Qin… - Journal of Functional …, 2023 - Elsevier
Melanin as a natural pigment widely exists in animals, plants, fungi and bacteria. In vivo and
in vitro tests have proven that melanin has a variety of health-promoting effects, such as …

Salvianolic acid B inhibits atherosclerosis and TNF-α-induced inflammation by regulating NF-κB/NLRP3 signaling pathway

Y Zhao, C Shao, H Zhou, L Yu, Y Bao, Q Mao, J Yang… - Phytomedicine, 2023 - Elsevier
Background Inflammation is critical in the pathophysiology of atherosclerosis (AS). The aim
of this study was to investigate the protective effect of salvianolic acid B (Sal B) on AS and to …

A review of the pharmacology and toxicology of aucubin

X Zeng, F Guo, D Ouyang - Fitoterapia, 2020 - Elsevier
Aucubin is an iridoid glycoside that is widely prevalent in traditional medicinal herbs, such
as Eucommia ulmoides Oliv., Aucuba japonica Thunb. and Plantago asiatica L. This review …

[HTML][HTML] Paeoniflorin alleviates AngII-induced cardiac hypertrophy in H9c2 cells by regulating oxidative stress and Nrf2 signaling pathway

S Ren, Y Wang, Y Zhang, P Yan, D Xiao, Y Zhao… - Biomedicine & …, 2023 - Elsevier
Cardiac hypertrophy is frequently associated with ventricular dysfunction and heart failure.
Paeoniflorin, has been widely used to treat cardiovascular dysfunction-related diseases …

Chemical Markers and Pharmacological Characters of Pelargonium graveolens Essential Oil from Palestine

N Jaradat, M Hawash, M Qadi, M Abualhasan… - Molecules, 2022 - mdpi.com
Pelargonium graveolens leaves are widely used in traditional medicine for relieving some
cardiovascular, dental, gastrointestinal, and respiratory disorders. They are also used as …

Gut-flora-dependent metabolite trimethylamine-N-oxide promotes atherosclerosis-associated inflammation responses by indirect ROS stimulation and signaling …

S Zhou, J Xue, J Shan, Y Hong, W Zhu, Z Nie, Y Zhang… - Nutrients, 2022 - mdpi.com
Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite after ingesting
dietary choline, has been identified as a novel risk factor for atherosclerosis through …