Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

Inflammatory myopathies, collectively known as myositis, are heterogeneous disorders
characterised by muscle inflammation, and frequently accompanied by extramuscular …

Accumulating data on cellular and molecular pathways help to develop novel therapeutic
strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic …

Inflammatory Muscle Diseases | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …

Type I interferons (IFNs) are essential mediators of antiviral responses. These cytokines
have been implicated in the pathogenesis of autoimmunity, most notably systemic lupus …

Objective This open‐label 12‐week study was conducted to evaluate the efficacy and safety
of tofacitinib, a JAK inhibitor, in treatment‐refractory active dermatomyositis (DM). Methods …

Idiopathic inflammatory myopathies (IIM) are a heterogenous family of diseases that can
affect the muscles, skin, lungs, and joints. There have been prior attempts to classify IIMs …

Systemic lupus erythematosus, Sjögren's syndrome, and dermatomyositis are systemic
autoimmune diseases that develop after environmental triggering of genetically susceptible …

Dermatomyositis (DM) is an idiopathic inflammatory myopathy that commonly manifests with
proximal muscle weakness and is associated with extramuscular pathology including …

Inflammation is an important contributor to the pathology of diseases implicated in skeletal
muscle dysfunction. A number of diseases and disorders including inflammatory myopathies …