Protein disulfide isomerase in redox cell signaling and homeostasis

FRM Laurindo, LA Pescatore… - Free Radical Biology and …, 2012 - Elsevier
Thiol proteins may potentially act as redox signaling adaptor proteins, adjusting reactive
oxygen species intermediates to specific signals and redox signals to cell homeostasis. In …

Diagnostic and prognostic potential of AKR1B10 in human hepatocellular carcinoma

JK DiStefano, B Davis - Cancers, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide.
Although diagnostic measures and surgical interventions have improved in recent years, the …

Combined functional genome survey of therapeutic targets for hepatocellular carcinoma

R Satow, M Shitashige, Y Kanai, F Takeshita… - Clinical Cancer …, 2010 - AACR
Purpose: The outcome of patients with advanced hepatocellular carcinoma (HCC) has
remained unsatisfactory. Patients with HCC suffer from chronic hepatitis or liver cirrhosis …

Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects

JH Kao, PJ Chen, DS Chen - Advances in cancer research, 2010 - Elsevier
Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, and more
than half of HCC patients are attributable to persistent hepatitis B virus (HBV) infections. The …

Identification and expression analysis of the aldo–ketoreductase1-B10 gene in primary malignant liver tumours

S Heringlake, M Hofdmann, A Fiebeler, MP Manns… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: The aim of our study was to search for highly up-regulated genes in
primary malignant liver tumours and to analyse their expression at the mRNA-and protein …

Aldo–keto reductase 1B10 and its role in proliferation capacity of drug-resistant cancers

T Matsunaga, Y Wada, S Endo, M Soda… - Frontiers in …, 2012 - frontiersin.org
The human aldo–keto reductase AKR1B10, originally identified as an aldose reductase-like
protein and human small intestine aldose reductase, is a cytosolic NADPH-dependent …

Pan‐Cancer Analysis of PDIA3: Identifying It as a Potential Biomarker for Tumor Prognosis and Immunotherapy

J Zhang, K Wang, T Hainisayimu… - Oxidative Medicine and …, 2022 - Wiley Online Library
Protein disulfide isomerase A3 (PDIA3) is a kind of thiol oxidoreductase with a wide range of
functions, and its expression is elevated in a variety of tumors, which is closely related to the …

SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome

MK Kashyap, HC Harsha, S Renuse… - Cancer biology & …, 2010 - Taylor & Francis
The identification of secreted proteins that are differentially expressed between non-
neoplastic and esophageal squamous cell carcinoma (ESCC) cells can provide potential …

Eight‐plex iTRAQ analysis of variant metastatic human prostate cancer cells identifies candidate biomarkers of progression: an exploratory study

A Glen, CA Evans, CS Gan, SS Cross, FC Hamdy… - The …, 2010 - Wiley Online Library
BACKGROUND Due to the heterogeneity in the biological behavior of prostate cancer,
biomarkers that can reliably distinguish indolent from aggressive disease are urgently …

Aldoketoreductase family 1B10 (AKR1B10) as a biomarker to distinguish hepatocellular carcinoma from benign liver lesions

KA Matkowskyj, H Bai, J Liao, W Zhang, H Li, S Rao… - Human pathology, 2014 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common highly aggressive malignant
tumors worldwide. Aldoketoreductase 1B10 (AKR1B10) was first isolated from HCC and …