Loss of intercalated cells (ITCs) in the mouse amygdala of Tshz1 mutants correlates with fear, depression, and social interaction phenotypes

J Kuerbitz, M Arnett, S Ehrman… - Journal of …, 2018 - Soc Neuroscience
The intercalated cells (ITCs) of the amygdala have been shown to be critical regulatory
components of amygdalar circuits, which control appropriate fear responses. Despite this …

Differential requirements of tubulin genes in mammalian forebrain development

E Bittermann, Z Abdelhamed, RP Liegel, C Menke… - PLoS …, 2019 - journals.plos.org
Tubulin genes encode a series of homologous proteins used to construct microtubules
which are essential for multiple cellular processes. Neural development is particularly reliant …

KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

N Homma, R Zhou, MI Naseer, AG Chaudhary… - Elife, 2018 - elifesciences.org
Kinesin super family protein 2A (KIF2A), an ATP-dependent microtubule (MT) destabilizer,
regulates cell migration, axon elongation, and pruning in the developing nervous system …

Developmental manganese neurotoxicity in rats: Cognitive deficits in allocentric and egocentric learning and memory

RM Amos-Kroohs, LL Davenport, N Atanasova… - Neurotoxicology and …, 2017 - Elsevier
Manganese (Mn) is an essential element but neurotoxic at higher exposure levels. The
effects of Mn overexposure (MnOE) on hippocampal and striatal-dependent learning and …

Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes

RK Garge, JM Laurent, AH Kachroo, EM Marcotte - Genetics, 2020 - academic.oup.com
Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from
Divergent Human Genes | Genetics | Oxford Academic Skip to Main Content Advertisement …

TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis

EL Ivanova, JG Gilet, V Sulimenko, A Duchon… - Nature …, 2019 - nature.com
De novo heterozygous missense variants in the γ-tubulin gene TUBG1 have been linked to
human malformations of cortical development associated with intellectual disability and …

Cellular and Molecular Changes During Aging in MEC: Unveiling the Role of Bglap3 Neurons in Cognitive Aging

C Miao, Q Cao, S Uzeen, S Cheng, Y Liu, J Liu, S Wen… - bioRxiv, 2024 - biorxiv.org
Aging-correlated cognitive declines, including deficiencies in spatial orientation and
memory, may reflect dysfunction in the hippocampus and medial entorhinal cortex (MEC) …

Maternal Germline Mosaicism of a de Novo TUBB2B Mutation Leads to Complex Cortical Dysplasia in Two Siblings

Ş Çitli, E Serdaroglu - Fetal and pediatric pathology, 2022 - Taylor & Francis
Introduction: Complex cortical dysplasia with other brain malformations-7 (aka
polymicrogyria) caused by mutations in TUBB2B gene is a clinically heterogeneous …

Genomic contributions to self-injurious behavior in autism spectrum disorder

IA Osei-Owusu - 2021 - jscholarship.library.jhu.edu
Self-injurious behavior is a serious behavioral disorder characterized by the infliction of
physical injury to the individual's own body, resulting in tissue damage ranging from minor to …

Functional Studies of Disease-Associated Variants in the Tubulin-Specific Chaperone D (TBCD) Gene

M Mariano - 2020 - research-repository.uwa.edu.au
During fetal brain development, the dynamic properties of microtubule (MT) cytoskeleton
underpin essential functions within fetal brain cells to regulate proliferation, migration, and …