Epithelial-mesenchymal transition (EMT) is a physiological program during which polarised,
immobile epithelial cells lose connection with their neighbours and are converted to …

Ovarian cancer is one of the deadliest gynecological malignancies among women. The
reason for this outcome is the frequent acquisition of cancer cell resistance to platinum …

FBXO28 is a member of F-box proteins that are the substrate receptors of SCF (SKP1,
CULLIN1, F-box protein) ubiquitin ligase complexes. Despite the implications of its role in …

Snail transcription factors play essential roles in embryonic development and participate in
many physiological processes. However, these genes have been implicated in the …

During human kidney development, cells of the proximal nephron gradually differentiate into
podocytes and parietal epithelial cells (PECs). Podocytes are terminally differentiated cells …

Background Metastatic disease is the major cause of cancer-related deaths. Increasing
evidence shows that primary tumor cells can promote metastasis by preparing the local …

Currently, cancer is still a leading cause of human death globally. Tumor deterioration
comprises multiple events including metastasis, therapeutic resistance and immune …

Background Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast
cancer. FAM3B, a secreted protein, has been extensively studied in various types of tumors …

The most frequent cancer among women and a significant contributor to mortality is breast
cancer. The CRISPR/Cas9 gene-editing tool has promising applications for BC drug …

Sažetak U razvoju ljudskog bubrega stanice proksimalnog dijela nefrona postupno se
diferenciraju u podocite i parijetalne epitelne stanice (PES). Podociti su terminalno …