Genetic, epigenetic, and environmental contributions to neural tube closure

JJ Wilde, JR Petersen, L Niswander - Annual review of genetics, 2014 - annualreviews.org
The formation of the embryonic brain and spinal cord begins as the neural plate bends to
form the neural folds, which meet and adhere to close the neural tube. The neural ectoderm …

Metal-dependent Ser/Thr protein phosphatase PPM family: Evolution, structures, diseases and inhibitors

R Kamada, F Kudoh, S Ito, I Tani, JIB Janairo… - Pharmacology & …, 2020 - Elsevier
Protein phosphatases and kinases control multiple cellular events including proliferation,
differentiation, and stress responses through regulating reversible protein phosphorylation …

Costunolide represses hepatic fibrosis through WW domain‐containing protein 2‐mediated Notch3 degradation

M Ge, H Liu, N Zhang, W Niu, Z Lu… - British journal of …, 2020 - Wiley Online Library
Background and Purpose This study investigates the antifibrotic activities and potential
mechanisms of costunolide (COS), a natural sesquiterpene compound. Experimental …

Genome-wide association study for conformation traits in three Danish pig breeds

TH Le, OF Christensen, B Nielsen… - Genetics Selection …, 2017 - Springer
Background Selection for sound conformation has been widely used as a primary approach
to reduce lameness and leg weakness in pigs. Identification of genomic regions that affect …

Genome-wide association study provides strong evidence of genes affecting the reproductive performance of Nellore beef cows

TP Melo, GMF De Camargo, LG De Albuquerque… - PLoS …, 2017 - journals.plos.org
Reproductive traits are economically important for beef cattle production; however, these
traits are still a bottleneck in indicine cattle since these animals typically reach puberty at …

PPM1G restricts innate immune signaling mediated by STING and MAVS and is hijacked by KSHV for immune evasion

K Yu, H Tian, H Deng - Science advances, 2020 - science.org
The adaptor proteins, STING and MAVS, are components of critical pathogen-sensing
pathways that induce innate immunity. Phosphorylation of either adaptor results in activation …

[PDF][PDF] Single-cell RNA-seq reveals dynamic transcriptome profiling in human early neural differentiation

Z Shang, D Chen, Q Wang, S Wang, Q Deng… - …, 2018 - academic.oup.com
Background Investigating cell fate decision and subpopulation specification in the context of
the neural lineage is fundamental to understanding neurogenesis and neurodegenerative …

[Retracted] Clinical Value of PPM1G Gene in Survival Prognosis and Immune Infiltration of Hepatocellular Carcinoma

Q Xiao, Z Cheng, W Kuang, H Wu… - Applied bionics and …, 2022 - Wiley Online Library
Objective. Liver cancer is one of the most common malignancies, but its prognosis is still
poor. Exploring potential biomarkers is an important direction of tumor research. We intend …

PPM 1G forms a PPP‐type phosphatase holoenzyme with B56δ that maintains adherens junction integrity

P Kumar, P Tathe, N Chaudhary, S Maddika - EMBO reports, 2019 - embopress.org
Serine/threonine phosphatases achieve substrate diversity by forming distinct holoenzyme
complexes in cells. Although the PPP family of serine/threonine phosphatase family …

High expression of PPM1G is associated with the progression and poor prognosis of hepatocellular carcinoma

DL Xiong, Q Li, H Wang, WL Jin, XM Fan… - Cancer …, 2022 - content.iospress.com
BACKGROUND: PPM1G, a member of the serine/threonine protease family,
dephosphorylates various proteins and may be involved in cancer development. The role …