Atherosclerosis and inflammation: insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

The role of sinusoidal endothelial cells in the axis of inflammation and cancer within the liver

AL Wilkinson, M Qurashi, S Shetty - Frontiers in physiology, 2020 - frontiersin.org
Liver sinusoidal endothelial cells (LSEC) form a unique barrier between the liver sinusoids
and the underlying parenchyma, and thus play a crucial role in maintaining metabolic and …

Digging into the 3D structure predictions of AlphaFold2 with low confidence: disorder and beyond

A Bruley, JP Mornon, E Duprat, I Callebaut - Biomolecules, 2022 - mdpi.com
AlphaFold2 (AF2) has created a breakthrough in biology by providing three-dimensional
structure models for whole-proteome sequences, with unprecedented levels of accuracy. In …

Amelioration of acute myocardial infarction injury through targeted ferritin nanocages loaded with an ALKBH5 inhibitor

P Cheng, H Han, F Chen, L Cheng, C Ma, H Huang… - Acta Biomaterialia, 2022 - Elsevier
The roles of m 6 A RNA methylation and mitochondrial metabolism in acute myocardial
infarction (AMI) remain unclear. In this study, we demonstrated that m 6 A RNA methylation …

[HTML][HTML] Cell-mediated and cell membrane-coated nanoparticles for drug delivery and cancer therapy

S Yaman, U Chintapula, E Rodriguez… - Cancer Drug …, 2020 - ncbi.nlm.nih.gov
Nanotechnology-based drug delivery platforms have been developed over the last two
decades because of their favorable features in terms of improved drug bioavailability and …

Mutant APC reshapes Wnt signaling plasma membrane nanodomains by altering cholesterol levels via oncogenic β-catenin

A Erazo-Oliveras, M Muñoz-Vega, M Mlih… - Nature …, 2023 - nature.com
Although the role of the Wnt pathway in colon carcinogenesis has been described
previously, it has been recently demonstrated that Wnt signaling originates from highly …

Panax quinquefolius (North American Ginseng) Polysaccharides as Immunomodulators: Current Research Status and Future Directions

R Ghosh, DL Bryant, AL Farone - Molecules, 2020 - mdpi.com
Panax quinquefolius (North American ginseng, NAG) is a popular medicinal plant used
widely in traditional medicine. NAG products are currently available in various forms such as …

Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26. ZEBOV/MVA-BN-Filo

F Blengio, H Hocini, L Richert, C Lefebvre, M Durand… - Cell Reports, 2023 - cell.com
Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …

Dynamics of phagocytosis mediated by phosphatidylserine

D Vorselen - Biochemical Society Transactions, 2022 - portlandpress.com
Phagocytosis triggered by the phospholipid phosphatidylserine (PS) is key for the removal of
apoptotic cells in development, tissue homeostasis and infection. Modulation of PS …

[PDF][PDF] Hologenomic insights into mammalian adaptations to myrmecophagy

SC Cheng, CB Liu, XQ Yao, JY Hu, TT Yin… - National Science …, 2023 - academic.oup.com
Highly specialized myrmecophagy (ant-and termite-eating) has independently evolved
multiple times in species of various mammalian orders and represents a textbook example …