Exosomal microRNAs in liquid biopsies: future biomarkers for prostate cancer

A Valentino, P Reclusa, R Sirera… - Clinical and translational …, 2017 - Springer
Prostate cancer is the second most diagnosed cancer in males in the world. Plasma
quantification of prostate-specific antigen substantially improved the early detection of …

[HTML][HTML] Prostate cancer bone metastases biology and clinical management

E Archer Goode, N Wang… - Oncology Letters, 2023 - spandidos-publications.com
Prostate cancer (PCa) is one of the most prominent causes of cancer‑related mortality in the
male population. A highly impactful prognostic factor for patients diagnosed with PCa is the …

The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression

B Yao, S Zhu, X Wei, MK Chen, Y Feng, Z Li, X Xu… - Molecular Cancer, 2022 - Springer
Abstract Background Prostate cancer (PCa) is the most frequently diagnosed malignancy in
men, and its mechanism remains poorly understood. Therefore, it is urgent to discover …

Identification of miR-187 and miR-182 as biomarkers of early diagnosis and prognosis in patients with prostate cancer treated with radical prostatectomy

I Casanova-Salas, J Rubio-Briones… - The Journal of …, 2014 - auajournals.org
Purpose: miRNAs are noncoding RNAs that negatively regulate target mRNA gene
expression. Aberrant miRNA expression is associated with prostate cancer pathogenesis …

[HTML][HTML] miRNAs as molecular biomarkers for prostate cancer

D Coradduzza, T Solinas, F Balzano, N Culeddu… - The Journal of Molecular …, 2022 - Elsevier
miRNAs are short noncoding RNAs able to regulate specific mRNA stability, thus influencing
target gene expression. Disrupted levels of several miRNAs have been associated with …

Biomarkers in localized prostate cancer

M Ferro, C Buonerba, D Terracciano, G Lucarelli… - Future …, 2016 - Taylor & Francis
Biomarkers can improve prostate cancer diagnosis and treatment. Accuracy of prostate-
specific antigen (PSA) for early diagnosis of prostate cancer is not satisfactory, as it is an …

[HTML][HTML] MiR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition

L Wang, G Song, W Tan, M Qi, L Zhang, J Chan, J Yu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
The metastastic cascade is a complex process that is regulated at multiple levels in prostate
cancer (PCa). Recent evidence suggests that microRNAs (miRNAs) are involved in PCa …

miRNA-205 nanoformulation sensitizes prostate cancer cells to chemotherapy

PKB Nagesh, P Chowdhury, E Hatami, VKN Boya… - Cancers, 2018 - mdpi.com
The therapeutic application of microRNA (s) in the field of cancer has generated significant
attention in research. Previous studies have shown that miR-205 negatively regulates …

Nucleic acid-based biomarkers in body fluids of patients with urologic malignancies

B Ralla, C Stephan, S Meller, D Dietrich… - Critical reviews in …, 2014 - Taylor & Francis
This review focuses on the promising potential of nucleic acids in body fluids such as blood
and urine as diagnostic, prognostic, predictive and monitoring biomarkers in urologic …

MicroRNA as new tools for prostate cancer risk assessment and therapeutic intervention: results from clinical data set and patients' samples

A Cannistraci, AL Di Pace, R De Maria… - BioMed research …, 2014 - Wiley Online Library
Prostate cancer (PCa) is one of the leading causes of cancer‐related death in men. Despite
considerable advances in prostate cancer early detection and clinical management …