Globally, depression is a leading cause of disability and has remained so for decades.
Antidepressant medications have suboptimal outcomes and are too frequently associated …

It has been hypothesized that one mechanism through which physical activity provides
benefits to cognition and mood is via increasing brain‐derived neurotrophic factor (BDNF) …

Background During the aging process, physical capabilities (eg, muscular strength) and
cognitive functions (eg, memory) gradually decrease. Regarding cognitive functions …

Engagement in regular bouts of exercise confers numerous positive effects on brain health
across the lifespan. Acute bouts of exercise transiently improve cognitive function, while long …

In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …

Exercise has multiple beneficial effects on health including decreasing the risk of
neurodegenerative diseases. Such effects are thought to be mediated (at least in part) by …

Different forms of physical activity—endurance, resistance or dynamic power—stimulate
cytokine release from various tissues to the bloodstream. Receptors for exercise-induced …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Background Due to the important role of follistatin (FLST), myostatin (MSTN) and growth
differentiation factor 11 (GDF11) in muscle mass regulation; alterations in the FLST to MSTN …

Movement and regular physical activity are two important factors that help the human body
prevent, reduce and treat different chronic diseases such as obesity, type 2 diabetes, heart …