[PDF][PDF] The implication of platelet activating factor in cancer growth and metastasis: potent beneficial role of PAF-inhibitors and antioxidants

AB Tsoupras, C Iatrou, C Frangia… - … Formerly Current Drug …, 2009 - researchgate.net
Cancer is one of the leading causes of death in Europe and United States. New blood
vessel formation penetrating into solid tumors seems to be required for their growth and …

Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity

Ł Pecio, S Pecio, T Mroczek, W Oleszek - Molecules, 2023 - mdpi.com
Based on the literature data from 1973 to 2022, this work summarizes reports on spiro-
flavonoids with a spiro-carbon at the center of their structure and how this affects their …

Metal‐Free Tandem Rearrangement/Lactonization: Access to 3,3‐Disubstituted Benzofuran‐2‐(3H)‐ones

M Santi, DMC Ould, J Wenz, Y Soltani… - Angewandte Chemie …, 2019 - Wiley Online Library
A novel metal‐free synthesis of 3, 3‐disubstituted benzofuran‐2‐(3H)‐ones through reacting
α‐aryl‐α‐diazoacetates with triarylboranes is presented. Initially, triarylboranes were …

Metabolite Profiling of “Green” Extracts of Cynara cardunculus subsp. scolymus, Cultivar “Carciofo di Paestum” PGI by 1H NMR and HRMS-Based Metabolomics

A Cerulli, M Masullo, C Pizza, S Piacente - Molecules, 2022 - mdpi.com
Globe artichoke (Cynara cardunculus L. var. scolymus L.), is a perennial plant widely
cultivated in the Mediterranean area, known for its edible part named capitula or heads. Its …

Chestnut shells (Italian cultivar “Marrone di Roccadaspide” PGI): Antioxidant activity and chemical investigation with in depth LC-HRMS/MSn rationalization of tannins

A Cerulli, A Napolitano, M Masullo, J Hošek… - Food Research …, 2020 - Elsevier
In Italy a particularly valuable chestnut is “Marrone di Roccadaspide”, a protected
geographical indication (PGI) product, deriving from a Castanea sativa cultivar, typical of …

Resveratrol as an inhibitor of carcinogenesis

JM Pezzuto - Pharmaceutical Biology, 2008 - Taylor & Francis
Given the high probability of developing cancer over the period of a normal life span, cancer
chemoprevention provides an attractive therapeutic strategy for the delay or reversal of this …

Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical …

S Fakhri, SZ Moradi, F Faraji, L Kooshki… - Cancer and Metastasis …, 2024 - Springer
Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …

Yucca schidigera extract modulates the lead-induced oxidative damage, nephropathy and altered inflammatory response and glucose homeostasis in Japanese …

MR Farag, M Alagawany, ME Abd El-Hack… - Ecotoxicology and …, 2018 - Elsevier
The present study was conducted to explore the toxic effects of lead (Pb) on the
physiological responses of Japanese quails and to investigate the potential modulatory role …

[HTML][HTML] The potential role of dietary platelet-activating factor inhibitors in cancer prevention and treatment

R Lordan, A Tsoupras, I Zabetakis - Advances in nutrition, 2019 - Elsevier
Cancer is the second leading cause of mortality worldwide. The role of unresolved
inflammation in cancer progression and metastasis is well established. Platelet-activating …

Polyphenols from root, tubercles and grains cropped in Brazil: Chemical and nutritional characterization and their effects on human health and diseases

D dos Santos Baião, C Silva de Freitas, L Paes Gomes… - Nutrients, 2017 - mdpi.com
Throughout evolution, plants have developed the ability to produce secondary phenolic
metabolites, which are important for their interactions with the environment, reproductive …