Immune responses in leishmaniasis: an overview

AC Costa-da-Silva, DO Nascimento… - Tropical medicine and …, 2022 - mdpi.com
Leishmaniasis is a parasitic, widespread, and neglected disease that affects more than 90
countries in the world. More than 20 Leishmania species cause different forms of …

[HTML][HTML] Microbiota in disease-transmitting vectors

J Wang, L Gao, S Aksoy - Nature Reviews Microbiology, 2023 - nature.com
Haematophagous arthropods, including mosquitoes, ticks, flies, triatomine bugs and lice
(here referred to as vectors), are involved in the transmission of various pathogens to …

Vector microbiota manipulation by host antibodies: the forgotten strategy to develop transmission-blocking vaccines

A Maitre, A Wu-Chuang, J Aželytė, V Palinauskas… - Parasites & vectors, 2022 - Springer
Human and animal pathogens that are transmitted by arthropods are a global concern,
particularly those vectored by ticks (eg Borrelia burgdorferi and tick-borne encephalitis virus) …

Advancements in understanding the molecular and immune mechanisms of Bartonella pathogenicity

X Jin, Y Gou, Y Xin, J Li, J Sun, T Li, J Feng - Frontiers in Microbiology, 2023 - frontiersin.org
Bartonellae are considered to be emerging opportunistic pathogens. The bacteria are
transmitted by blood-sucking arthropods, and their hosts are a wide range of mammals …

Metabolic interactions between disease-transmitting vectors and their microbiota

X Song, Z Zhong, L Gao, BL Weiss, J Wang - Trends in Parasitology, 2022 - cell.com
Disease-transmitting vectors are living organisms that pass infectious agents from one
animal/human to another. The epidemiologically important vectors are usually …

From infection to death: an overview of the pathogenesis of Visceral Leishmaniasis

CHN Costa, KP Chang, DL Costa, FVM Cunha - Pathogens, 2023 - mdpi.com
Kala-azar, also known as visceral leishmaniasis (VL), is a disease caused by Leishmania
infantum and L. donovani. Patients experience symptoms such as fever, weight loss …

A review on new natural and synthetic anti-leishmanial chemotherapeutic agents and current perspective of treatment approaches.

N Majumder, A Banerjee, S Saha - Acta Tropica, 2023 - Elsevier
Leishmaniases are considered among the most neglected yet dangerous parasitic diseases
worldwide. According to the recent WHO report (Weekly Epidemiological Record, Sep …

The Therapeutic Effects of Curcumin-coated Gold Nanoparticle Against Leishmania Major Causative Agent of Zoonotic Cutaneous Leishmaniasis (ZCL): An In Vitro …

SM Amini, R Hadighi, M Najm, M Alipour… - Current …, 2023 - Springer
We synthesized and characterized curcumin-coated gold nanoparticles (Cur@ AuNPs) and
investigated their stability, cytotoxicity, leishmanicidal activity in in vitro and in in vivo …

[HTML][HTML] Leishmania genetic exchange is mediated by IgM natural antibodies

TD Serafim, E Iniguez, ABF Barletta, P Cecilio… - Nature, 2023 - nature.com
Host factors that mediate Leishmania genetic exchange are not well defined. Here we
demonstrate that natural IgM (IgMn),,–antibodies mediate parasite genetic exchange by …

Revisiting Leishmania GP63 host cell targets reveals a limited spectrum of substrates

MM Guay-Vincent, C Matte, AM Berthiaume… - PLoS …, 2022 - journals.plos.org
Colonization of host phagocytic cells by Leishmania metacyclic promastigotes involves
several parasite effectors, including the zinc-dependent metalloprotease GP63. The major …