The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

Monocytes and macrophages play a critical role in tissue development, homeostasis, and
injury repair. These innate immune cells participate in guiding vascular remodeling …

Macrophages are key contributors to vascularization, but the mechanisms behind their
actions are not understood. Here, we show that diverse macrophage phenotypes have …

Angiogenesis and lymphangiogenesis often occur in response to tissue injury or in the
presence of pathology (eg, cancer), and it is these types of environments in which …

Successful tissue repair requires the activities of myeloid cells such as monocytes and
macrophages that guide the progression of inflammation and healing outcome …

Macrophages and endothelial cells (ECs) have essential roles in physiological and
pathological conditions by regulating inflammation, vascularization and tissue remodelling …

Immune cells have emerged as powerful regulators of regenerative as well as pathological
processes. The vast majority of regenerative immunoengineering efforts have focused on …

Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

Inflammation is a response to infections or tissue injuries. Inflammation was once defined by
clinical signs, later by the presence of leukocytes, and nowadays by expression of …

Ischaemia of the heart and limbs attributable to compromised blood supply is a major cause
of mortality and morbidity. The mechanisms of functional angiogenesis remain poorly …