Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

F Ng, M Berk, O Dean, AI Bush - International Journal of …, 2008 - academic.oup.com
Oxidative stress has been implicated in the pathogenesis of diverse disease states, and may
be a common pathogenic mechanism underlying many major psychiatric disorders, as the …

[图书][B] Oxidation and antioxidants in organic chemistry and biology

ET Denisov, IB Afanas' ev - 2005 - taylorfrancis.com
Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Meta-analysis of oxidative stress in schizophrenia

J Flatow, P Buckley, BJ Miller - Biological psychiatry, 2013 - Elsevier
Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …

Oxidative stress in schizophrenia: an integrated approach

BKY Bitanihirwe, TUW Woo - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
Oxidative stress has been suggested to contribute to the pathophysiology of schizophrenia.
In particular, oxidative damage to lipids, proteins, and DNA as observed in schizophrenia is …

Antioxidants as potential therapeutics for neuropsychiatric disorders

CD Pandya, KR Howell, A Pillai - Progress in Neuro-Psychopharmacology …, 2013 - Elsevier
Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …

Oxidative stress in schizophrenia

M Boskovic, T Vovk, B Kores Plesnicar… - Current …, 2011 - ingentaconnect.com
Increasing evidence indicates that oxidative damage exists in schizophrenia. Available
literature about possible mechanisms of oxidative stress induction was reviewed …

Implications for reactive oxygen species in schizophrenia pathogenesis

M Koga, AV Serritella, A Sawa, TW Sedlak - Schizophrenia research, 2016 - Elsevier
Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

Viral infection, inflammation and schizophrenia

RE Kneeland, SH Fatemi - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
Schizophrenia is a severe neurodevelopmental disorder with genetic and environmental
etiologies. Prenatal viral/bacterial infections and inflammation play major roles in the …

Glutathione: a novel treatment target in psychiatry

M Berk, F Ng, O Dean, S Dodd, AI Bush - Trends in pharmacological …, 2008 - cell.com
There is accumulating evidence for oxidative stress mechanisms as common
pathophysiological pathways in diverse psychiatric disorders, which offers novel treatment …

Neuronal nitric oxide synthase (NOS1) and its adaptor, NOS1AP, as a genetic risk factors for psychiatric disorders

F Freudenberg, A Alttoa, A Reif - Genes, Brain and Behavior, 2015 - Wiley Online Library
Nitric oxide (NO) is a gaseous transmitter produced by nitric oxide synthases (NOSs). The
neuronal isoform (NOS‐I, encoded by NOS1) is the main source of NO in the central nervous …