Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis
Lateral flow assays (LFAs) are paper-based point-of-care (POC) diagnostic tools that are
widely used because of their low cost, ease of use, and rapid format. Unfortunately …
widely used because of their low cost, ease of use, and rapid format. Unfortunately …
Nucleic acid tests for clinical translation
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
Isothermal amplification of nucleic acids
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
Diverse applications of nanomedicine
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …
health-related issues continues to receive increasing interest. Research in nanomedicine …
Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics
Abstract The coronavirus disease 2019 (COVID-19) has extensively promoted the
application of nucleic acid testing technology in the field of clinical testing. The most widely …
application of nucleic acid testing technology in the field of clinical testing. The most widely …
Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …
LAMP-on-a-chip: Revising microfluidic platforms for loop-mediated DNA amplification
Nucleic acid amplification for the detection of infectious diseases, food pathogens, or
assessment of genetic disorders require a laboratory setting with specialized equipment and …
assessment of genetic disorders require a laboratory setting with specialized equipment and …
Polymerase chain reaction in microfluidic devices
The invention of the polymerase chain reaction (PCR) has caused a revolution in molecular
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
biology, giving access to a method of amplifying deoxyribonucleic acid (DNA) molecules …
Reagents-loaded, automated assay that integrates recombinase-aided amplification and Cas12a nucleic acid detection for a point-of-care test
Y Chen, Y Mei, X Zhao, X Jiang - Analytical chemistry, 2020 - ACS Publications
Point-of-care testing for nucleic acid that combines amplification and readout is in great
demand. This report integrates recombinase-aided amplification (RAA) with the clustered …
demand. This report integrates recombinase-aided amplification (RAA) with the clustered …
Microfluidics for biomedical analysis
Y Yang, Y Chen, H Tang, N Zong, X Jiang - Small methods, 2020 - Wiley Online Library
Many new techniques and materials have been applied to microfluidic systems in the past
decade, and integrated microfluidic chips have become powerful platforms for realizing …
decade, and integrated microfluidic chips have become powerful platforms for realizing …