[HTML][HTML] Formulation and evaluation of Ocimum basilicum-based emulgel for wound healing using animal model

BA Khan, S Ullah, MK Khan, SM Alshahrani… - Saudi pharmaceutical …, 2020 - Elsevier
The main aim of the topically applied drugs is to provide local drug contact to the skin and
minimize general absorption of drugs. Ocimum basilicum (OB) is popular for folk medicines …

Poncirin attenuates CCL4-induced liver injury through inhibition of oxidative stress and inflammatory cytokines in mice

H Ullah, A Khan, MW Baig, N Ullah, N Ahmed… - … medicine and therapies, 2020 - Springer
Background In the present study, the poncirin which is flavonoid-7-o-glycosides (isolated
from the Poncirus trifoliata) in nature was evaluated against the Carbon tetra chloride …

Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting NF-κβ pathway

E Sana, M Zeeshan, QU Ain, AU Khan, I Hussain… - …, 2021 - Taylor & Francis
Aim: To fabricate and evaluate curcumin-loaded transfersomes (Cur-TF) for the targeted
delivery and enhanced therapeutic efficacy of curcumin for the treatment of rheumatoid …

Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of inflammatory mediators correlates with increased Nrf2 protein …

H Ali, A Khan, J Ali, H Ullah, A Khan, H Ali… - BMC Pharmacology and …, 2020 - Springer
Background Acute lung injury (ALI) together with acute respiratory distress syndrome
(ARDS) are associated with high rate of mortality and morbidity in patients. In the current …

Formulation Development, Characterization, and Evaluation of a Novel Dexibuprofen-Capsaicin Skin Emulgel with Improved In Vivo Anti-inflammatory and Analgesic …

IK Burki, MK Khan, BA Khan, B Uzair, VA Braga… - AAPS …, 2020 - Springer
Transdermal application of analgesics allows efficient and painless delivery of medication
with minimum side effect. This study was designed with the aim to formulate and …

[HTML][HTML] Suppression of TRPV1/TRPM8/P2Y nociceptors by withametelin via downregulating MAPK signaling in mouse model of vincristine-induced neuropathic pain

A Khan, B Shal, AU Khan, R Ullah, MW Baig… - International journal of …, 2021 - mdpi.com
Vincristine (VCR) is a widely used chemotherapy drug that induced peripheral painful
neuropathy. Yet, it still lacks an ideal therapeutic strategy. The transient receptor potential …

Anti-neuropathic pain activity of Ajugarin-I via activation of Nrf2 signaling and inhibition of TRPV1/TRPM8 nociceptors in STZ-induced diabetic neuropathy

A Khan, F Wang, B Shal, AU Khan, SS Zahra… - Pharmacological …, 2022 - Elsevier
This study aimed to investigate the anti-neuropathic pain activity and its underlying
molecular mechanism of Ajugarin-I (Aju-I) in a rat model of diabetic neuropathic pain. The …

Withametelin, a novel phytosterol, alleviates neurological symptoms in EAE mouse model of multiple sclerosis via modulation of Nrf2/HO-1 and TLR4/NF-κB signaling

A Khan, B Shal, AU Khan, T Bibi, S ul Islam… - Neurochemistry …, 2021 - Elsevier
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system (CNS) that remains incurable. Withametelin (WMT), a phytosterol, showed …

[HTML][HTML] Anti-inflammatory and analgesic potential of leaf extract of Justicia adhatoda L.(Acanthaceae) in Carrageenan and Formalin-induced models by targeting …

A Basit, T Shutian, A Khan, SM Khan… - Biomedicine & …, 2022 - Elsevier
Plants are regarded as a valuable and inexpensive source of new drug development, and a
variety of plant compounds are now being used in clinical trials to treat a variety of ailments …

Chemical profiling of Justicia vahlii Roth.(Acanthaceae) using UPLC-QTOF-MS and GC-MS analysis and evaluation of acute oral toxicity, antineuropathic and …

A Basit, S Ahmad, A Naeem, M Usman, I Ahmed… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Justicia vahlii Roth.(Acanthaceae), also called as
kodasoori and bhekkar is an annual therophyte erect or decumbent herb used traditionally …