Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

M Agrawal, S Saraf, S Saraf, SG Antimisiaris… - Journal of controlled …, 2018 - Elsevier
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …

Classification, processing and application of hydrogels: A review

F Ullah, MBH Othman, F Javed, Z Ahmad… - Materials Science and …, 2015 - Elsevier
This article aims to review the literature concerning the choice of selectivity for hydrogels
based on classification, application and processing. Super porous hydrogels (SPHs) and …

Basic concepts and recent advances in nanogels as carriers for medical applications

I Neamtu, AG Rusu, A Diaconu, LE Nita, AP Chiriac - Drug delivery, 2017 - Taylor & Francis
Nanogels in biomedical field are promising and innovative materials as dispersions of
hydrogel nanoparticles based on crosslinked polymeric networks that have been called as …

Hydrogels in a historical perspective: From simple networks to smart materials

SJ Buwalda, KWM Boere, PJ Dijkstra, J Feijen… - Journal of controlled …, 2014 - Elsevier
Over the past decades, significant progress has been made in the field of hydrogels as
functional biomaterials. Biomedical application of hydrogels was initially hindered by the …

An injectable and thermosensitive hydrogel: Promoting periodontal regeneration by controlled-release of aspirin and erythropoietin

X Xu, Z Gu, X Chen, C Shi, C Liu, M Liu, L Wang… - Acta biomaterialia, 2019 - Elsevier
Periodontitis is an inflammatory disease induced by complex interactions between host
immune system and plaque microorganism. Alveolar bone resorption caused by …

Alginate-based hydrogels and tubes, as biological macromolecule-based platforms for peripheral nerve tissue engineering: a review

WK Abdelbasset, SA Jasim, SK Sharma… - Annals of Biomedical …, 2022 - Springer
Unlike the central nervous system, the peripheral nervous system (PNS) has an inherent
capacity to regenerate following injury. However, in the case of large nerve defects where …

Enzyme-responsive polymeric assemblies, nanoparticles and hydrogels

J Hu, G Zhang, S Liu - Chemical Society Reviews, 2012 - pubs.rsc.org
Being responsive and adaptive to external stimuli is an intrinsic feature characteristic of all
living organisms and soft matter. Specifically, responsive polymers can exhibit reversible or …

Boronic acid-containing hydrogels: synthesis and their applications

Y Guan, Y Zhang - Chemical Society Reviews, 2013 - pubs.rsc.org
Boronic acid-containing hydrogels are important intelligent materials. With the introduction of
boronic acid functionality, these hydrogels exhibit a lot of interesting properties, such as …

Environment sensitive hydrogels for drug delivery applications

D Qureshi, SK Nayak, S Maji, A Anis, D Kim… - European Polymer …, 2019 - Elsevier
Over the last few decades, hydrogels have attracted the considerable interest of researchers
for crafting potential controlled drug delivery systems. It may be attributed to their high water …

Injectable polymeric hydrogels for the delivery of therapeutic agents: A review

QV Nguyen, JH Park, DS Lee - European Polymer Journal, 2015 - Elsevier
Since drug delivery systems have become one of the most promising areas of human health
related research, the applications of biomaterials such as hydrogels have been widely …