The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Western diet: implications for brain function and behavior

I López-Taboada, H González-Pardo… - Frontiers in …, 2020 - frontiersin.org
The Western diet (WD) pattern characterized by high daily intake of saturated fats and
refined carbohydrates often leads to obesity and overweight, and it has been linked to …

Separate gut-brain circuits for fat and sugar reinforcement combine to promote overeating

M McDougle, A de Araujo, A Singh, M Yang, I Braga… - Cell metabolism, 2024 - cell.com
Food is a powerful natural reinforcer that guides feeding decisions. The vagus nerve
conveys internal sensory information from the gut to the brain about nutritional value; …

Liraglutide restores impaired associative learning in individuals with obesity

R Hanssen, L Rigoux, B Kuzmanovic, S Iglesias… - Nature …, 2023 - nature.com
Survival under selective pressure is driven by the ability of our brain to use sensory
information to our advantage to control physiological needs. To that end, neural circuits …

High-fat food biases hypothalamic and mesolimbic expression of consummatory drives

CM Mazzone, J Liang-Guallpa, C Li, NS Wolcott… - Nature …, 2020 - nature.com
Maintaining healthy body weight is increasingly difficult in our obesogenic environment.
Dieting efforts are often overpowered by the internal drive to consume energy-dense foods …

The sensory properties and metabolic impact of natural and synthetic sweeteners

MR Mora, R Dando - … Reviews in Food Science and Food …, 2021 - Wiley Online Library
The global rise in obesity, type II diabetes, and other metabolic disorders in recent years has
been attributed in part to the overconsumption of added sugars. Sugar reduction strategies …

Rethinking food reward

IE de Araujo, M Schatzker… - Annual review of …, 2020 - annualreviews.org
The conscious perception of the hedonic sensory properties of caloric foods is commonly
believed to guide our dietary choices. Current and traditional models implicate the …

Cellular activity in insular cortex across seconds to hours: Sensations and predictions of bodily states

Y Livneh, ML Andermann - Neuron, 2021 - cell.com
Our wellness relies on continuous interactions between our brain and body: different organs
relay their current state to the brain and are regulated, in turn, by descending visceromotor …

[HTML][HTML] Short-term consumption of sucralose with, but not without, carbohydrate impairs neural and metabolic sensitivity to sugar in humans

JR Dalenberg, BP Patel, R Denis, MG Veldhuizen… - Cell Metabolism, 2020 - cell.com
There is a general consensus that overconsumption of sugar-sweetened beverages
contributes to the prevalence of obesity and related comorbidities such as type 2 diabetes …

Integrative hedonic and homeostatic food intake regulation by the central nervous system: insights from neuroimaging

A Campos, JD Port, A Acosta - Brain sciences, 2022 - mdpi.com
Food intake regulation in humans is a complex process controlled by the dynamic
interaction of homeostatic and hedonic systems. Homeostatic regulation is controlled by …