Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Anti-inflammatory drugs as anticancer agents

S Zappavigna, AM Cossu, A Grimaldi… - International journal of …, 2020 - mdpi.com
Inflammation is strictly associated with cancer and plays a key role in tumor development
and progression. Several epidemiological studies have demonstrated that inflammation can …

Multiple myeloma: diagnosis and treatment

SV Rajkumar, S Kumar - Mayo Clinic Proceedings, 2016 - Elsevier
The diagnosis and treatment of multiple myeloma has changed dramatically in the past
decade. The disease definition has been updated to include highly specific biomarkers in …

Cancer-associated venous thromboembolism: burden, mechanisms, and management

C Ay, I Pabinger, AT Cohen - Thrombosis and haemostasis, 2017 - thieme-connect.com
Venous thromboembolism (VTE) is a significant health problem in the general population
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …

Multiple myeloma: 2016 update on diagnosis, risk‐stratification, and management

SV Rajkumar - American journal of hematology, 2016 - Wiley Online Library
Multiple myeloma accounts for approximately 10% of hematologic malignancies. The
diagnosis requires≥ 10% clonal bone marrow plasma cells or a biopsy proven …

Continued improvement in survival in multiple myeloma: changes in early mortality and outcomes in older patients

SK Kumar, A Dispenzieri, MQ Lacy, MA Gertz, FK Buadi… - Leukemia, 2014 - nature.com
Therapy for multiple myeloma (MM) has markedly changed in the past decade with the
introduction of new drugs, but it is not clear whether the improvements have been sustained …

Multiple myeloma: 2020 update on diagnosis, risk‐stratification and management

SV Rajkumar - American journal of hematology, 2020 - Wiley Online Library
Disease overview Multiple myeloma accounts for approximately 10% of hematologic
malignancies. Diagnosis The diagnosis requires≥ 10% clonal bone marrow plasma cells or …

Risk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group study

SK Kumar, JH Lee, JJ Lahuerta, G Morgan… - Leukemia, 2012 - nature.com
Promising new drugs are being evaluated for treatment of multiple myeloma (MM), but their
impact should be measured against the expected outcome in patients failing current …

Cancer therapy–associated thrombosis

SP Grover, YM Hisada, RS Kasthuri… - … , and vascular biology, 2021 - Am Heart Assoc
Patients with cancer have an increased risk of both arterial and venous thrombotic events
compared with the general population. Both the site and stage of cancer are known to …

Cardiovascular complications of cancer therapy: incidence, pathogenesis, diagnosis, and management

ETH Yeh, CL Bickford - Journal of the American College of Cardiology, 2009 - jacc.org
Cancer treatment today employs a combination of chemotherapy, radiotherapy, and surgery
to prolong life and provide cure. However, many of these treatments can cause …