OR in healthcare: A European perspective

S Brailsford, J Vissers - European journal of operational research, 2011 - Elsevier
The European Working Group “Operational Research Applied to Health Services”(ORAHS)
is one of the domain specific EURO Working Groups organized by EURO–the European …

iCycle: Integrated, multicriterial beam angle, and profile optimization for generation of coplanar and noncoplanar IMRT plans

S Breedveld, PRM Storchi, PWJ Voet… - Medical …, 2012 - Wiley Online Library
Purpose: To introduce iCycle, a novel algorithm for integrated, multicriterial optimization of
beam angles, and intensity modulated radiotherapy (IMRT) profiles. Methods: A multicriterial …

Combining radial basis function surrogates and dynamic coordinate search in high-dimensional expensive black-box optimization

RG Regis, CA Shoemaker - Engineering Optimization, 2013 - Taylor & Francis
This article presents the DYCORS (DYnamic COordinate search using Response Surface
models) framework for surrogate-based optimization of HEB (High-dimensional, Expensive …

Reflections on beam configuration optimization for intensity-modulated proton therapy

W Cao, H Rocha, R Mohan, G Lim… - Physics in Medicine …, 2022 - iopscience.iop.org
Presumably, intensity-modulated proton radiotherapy (IMPT) is the most powerful form of
proton radiotherapy. In the current state of the art, IMPT beam configurations (ie the number …

Stochastic radial basis function algorithms for large-scale optimization involving expensive black-box objective and constraint functions

RG Regis - Computers & Operations Research, 2011 - Elsevier
This paper presents a new algorithm for derivative-free optimization of expensive black-box
objective functions subject to expensive black-box inequality constraints. The proposed …

A quasi-multistart framework for global optimization of expensive functions using response surface models

RG Regis, CA Shoemaker - Journal of Global Optimization, 2013 - Springer
We present the AQUARS (A QUAsi-multistart Response Surface) framework for finding the
global minimum of a computationally expensive black-box function subject to bound …

Neighborhood search approaches to beam orientation optimization in intensity modulated radiation therapy treatment planning

DM Aleman, A Kumar, RK Ahuja, HE Romeijn… - Journal of Global …, 2008 - Springer
The intensity modulated radiation therapy (IMRT) treatment planning problem consists of
several subproblems which are typically solved sequentially. We seek to combine two of the …

Trust regions in Kriging-based optimization with expected improvement

RG Regis - Engineering optimization, 2016 - Taylor & Francis
The Kriging-based Efficient Global Optimization (EGO) method works well on many
expensive black-box optimization problems. However, it does not seem to perform well on …

A general stochastic algorithmic framework for minimizing expensive black box objective functions based on surrogate models and sensitivity analysis

Y Wang, CA Shoemaker - arXiv preprint arXiv:1410.6271, 2014 - arxiv.org
We are focusing on bound constrained global optimization problems, whose objective
functions are computationally expensive black-box functions and have multiple local …

A two-phase method for selecting IMRT treatment beam angles: Branch-and-Prune and local neighborhood search

GJ Lim, W Cao - European Journal of Operational Research, 2012 - Elsevier
This paper presents a new two-phase solution approach to the beam angle and fluence map
optimization problem in Intensity Modulated Radiation Therapy (IMRT) planning. We …