Sleep is an essential component of overall human health but is so tightly regulated that
when disrupted can cause or worsen certain ailments. An important part of this process is …

Bipolar disorder is one of the severe mental diseases. Its high misdiagnosis rate and long-
time delayed diagnosis are related to the fact that the diagnosis procedure is mainly …

Salivary biomarkers are increasingly being used as an alternative to diagnose and monitor
the progression of various diseases due to their ease of use, on site application, non …

Background Circadian dysregulation has long been thought to be a key component in the
pathophysiology of bipolar disorder (BD). However, it remains unclear whether this …

Introduction: Early detection and intervention in bipolar disorder (BD) might reduce illness
severity, slow its progression, and, in specific cases, even ward off the full-blown disorder …

Bipolar disorder is a highly heritable and functionally impairing disease. The recognition and
intervention of BD especially that characterized by early onset remains challenging. Risk …

Abstract In this paper, 2, 3-naphthalenedialdehyde (2, 3-Nda) was selected as color reagent
with colorimetric and fluorometric assay for detecting melatonin in human saliva. 2, 3 …

Introduction There are numerous reports on the facilitatory role of the pineal gland (PG) in
brain function, and the size this structure is suggested to be associated with its proper …