Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases

Z Liu, Y Sun, Z Qi, L Cao, S Ding - Cell & bioscience, 2022 - Springer
Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …

Mitochondria-derived cell-to-cell communication

ZAA Dache, AR Thierry - Cell Reports, 2023 - cell.com
In addition to their intracellular mobility, mitochondria and their components can exist
outside the cells from which they originate. As a result, they are capable of acting on non …

[HTML][HTML] Mitochondria on the move: Horizontal mitochondrial transfer in disease and health

LF Dong, J Rohlena, R Zobalova, Z Nahacka… - Journal of Cell …, 2023 - rupress.org
Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Renal damage induced by cadmium and its possible therapy by mitochondrial transplantation

EY Hernández-Cruz, I Amador-Martínez… - Chemico-biological …, 2022 - Elsevier
Cadmium (Cd) is one of the most toxic metals without biological function, and its
accumulation in living organisms has been reported. The kidney is a target organ in Cd …

Mitochondria can cross cell boundaries: An overview of the biological relevance, pathophysiological implications and therapeutic perspectives of intercellular …

D Valenti, RA Vacca, L Moro, A Atlante - International journal of molecular …, 2021 - mdpi.com
Mitochondria are complex intracellular organelles traditionally identified as the
powerhouses of eukaryotic cells due to their central role in bioenergetic metabolism. In …

Mitochondrial proteome research: the road ahead

ZN Baker, P Forny, DJ Pagliarini - Nature Reviews Molecular Cell …, 2024 - nature.com
Mitochondria are multifaceted organelles with key roles in anabolic and catabolic
metabolism, bioenergetics, cellular signalling and nutrient sensing, and programmed cell …

Mitochondrial function in development and disease

MP Rossmann, SM Dubois… - Disease models & …, 2021 - journals.biologists.com
Mitochondria are organelles with vital functions in almost all eukaryotic cells. Often
described as the cellular 'powerhouses' due to their essential role in aerobic oxidative …

[HTML][HTML] Inter and intracellular mitochondrial transfer: Future of mitochondrial transplant therapy in Parkinson's disease

R Jain, N Begum, KP Tryphena, SB Singh… - Biomedicine & …, 2023 - Elsevier
Parkinson's disease (PD) is marked by the gradual degeneration of dopaminergic neurons
and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various …

Inter and Intracellular mitochondrial trafficking in health and disease

S Shanmughapriya, D Langford… - Ageing research …, 2020 - Elsevier
Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …

Mitochondrial dysfunction and Parkinson's disease: pathogenesis and therapeutic strategies

S Moradi Vastegani, A Nasrolahi, S Ghaderi… - Neurochemical …, 2023 - Springer
Parkinson's disease (PD) is a common age-related neurodegenerative disorder whose
pathogenesis is not completely understood. Mitochondrial dysfunction and increased …