Advances in nickel-catalyzed cross-coupling reactions have expanded the chemical space
of accessible structures and enabled new synthetic disconnections. The unique properties of …

Conspectus Transition-metal-catalyzed C–O bond activation provides a useful strategy for
utilizing alcohol-and phenol-derived electrophiles in cross-coupling reactions, which has …

Ni-catalyzed cross-electrophile coupling reactions have emerged as appealing methods to
construct organic molecules without the use of stoichiometric organometallic reagents. The …

As an advance in hydrofunctionalization, we herein report that alcohols add to 1, 3-dienes
with high regio-and enantioselectivity. Using Ni-DuPhos, we access enantioenriched allylic …

We report a nickel-catalyzed cross-electrophile coupling reaction of aryl chlorides and
heteroaryl chlorides enabled by a synergistic combination consisting of halide effects and …

Cross-electrophile coupling reactions of two Csp3–X bonds remain challenging. Herein we
report an intramolecular nickel-catalyzed cross-electrophile coupling reaction of 1, 3-diol …

Methods to form carbon–carbon bonds efficiently and with control of stereochemistry are
critical for the construction of complex molecules. Cross-coupling reactions are among the …

The use of a simple stilbene ligand has enabled a stereospecific Suzuki–Miyaura cross-
coupling of tertiary benzylic carboxylates, including those lacking naphthyl substituents. This …

Understanding mechanistic details of the nickel-catalyzed coupling reactions of Csp3
alcohol derivatives is key to developing selective reactions of this widely prevalent functional …

Palladium-catalyzed allylic sulfonylation of tertiary allylic carbonates with sodium sulfinates
provides a first general asymmetric approach towards the synthesis of sterically encumbered …