Hematogones: an overview

SP Chantepie, E Cornet, V Salaün, O Reman - Leukemia Research, 2013 - Elsevier
Hematogones were initially described as mysterious cells in bone marrow smears more than
70 years ago. These cells are normal bone marrow B-lymphocyte precursors with properties …

Relapse assessment following allogeneic SCT in patients with MDS and AML

M Christopeit, N Kröger, T Haferlach, U Bacher - Annals of hematology, 2014 - Springer
Options to pre-emptively treat impending relapse of myelodysplastic syndromes (MDS) and
acute myeloid leukaemia (AML) after allogeneic haematopoietic stem cell transplantation …

Quantitation of hematogones at the time of engraftment is a useful prognostic indicator in allogeneic hematopoietic stem cell transplantation

T Shima, T Miyamoto, Y Kikushige… - Blood, The Journal …, 2013 - ashpublications.org
Transient marrow expansion of normal B-cell precursors, termed hematogones, is
occasionally observed after hematopoietic stem cell transplantation (HSCT). To understand …

The prognostic significance of hematogones in childhood B‐cell acute lymphoblastic leukemia

S Arabi, S Yousefian, A Kavosh… - Pediatric Blood & …, 2023 - Wiley Online Library
Background Recent studies have demonstrated hematogones (HGs) expansion to be
associated with favorable outcomes in hematological diseases, especially in patients with …

[HTML][HTML] Impact of bone marrow hematogones on umbilical cord blood transplantation outcomes in patients with acute myeloid leukemia

T Honebrink, V Dayton, MJ Burke, K Larsen… - Biology of Blood and …, 2012 - Elsevier
Early after umbilical cord blood transplantation, patients show marked differences in bone
marrow (BM) hematogone percentages. Little is known about whether these differences are …

The clinicopathologic significance of lymphocyte subsets in acute myeloid leukemia

M Alcasid, L Ma, JR Gotlib, DA Arber… - … journal of laboratory …, 2017 - Wiley Online Library
Introduction While the role of the immune system in altering and modulating the progression
of solid tumors is well studied, the impact of the immune system on the outcome and …

[HTML][HTML] Hematogones predict better outcome in allogeneic hematopoietic stem cell transplantation irrespective of graft sources

T Ishio, J Sugita, T Tateno, D Hidaka, E Hayase… - Biology of Blood and …, 2018 - Elsevier
Benign precursors of B lymphocytes, termed hematogones, are observed in the regenerative
state of hematopoiesis following chemotherapy or allogeneic hematopoietic stem cell …

The importance of immunophenotyping by flow cytometry in distinction between hematogones and B lymphoblasts

AB Wohlfahrt, L Hannel, LZ Oliveira… - Jornal brasileiro de …, 2015 - SciELO Brasil
Hematogones are normal B-lineage lymphoid precursors in the bone marrow. B
lymphoblasts are immature neoplastic cells present in patients with precursor B-cell acute …

Clinical impact of hematogones on outcomes of allogeneic hematopoietic stem cell transplantation

N Doki, K Haraguchi, T Hagino, A Igarashi… - Annals of …, 2015 - Springer
Increased levels of normal B cell precursors, termed hematogones (HGs), are observed in
regenerating bone marrow after chemotherapy or hematopoietic stem cell transplantation …

Prognostic factors contributing to the survival of hematopoietic stem cell transplantation in the general population with leukemia: a systematic review

K Tayuwijaya, SL Raharja, M Rosana… - Regenerative …, 2023 - Springer
Purpose Hematopoietic stem cell transplantation (HSCT) offers new hope for improving the
outcome of leukemic patients who have failed chemotherapy or irradiation therapy. To our …