The ABC transporters in lipid flux and atherosclerosis

I Voloshyna, AB Reiss - Progress in lipid research, 2011 - Elsevier
Atherosclerotic cardiovascular disease is the leading cause for morbidity and mortality in the
United States and in many other countries. Dysfunctional lipid homeostasis plays a central …

Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis

A Leroux, G Ferrere, V Godie, F Cailleux… - Journal of …, 2012 - Elsevier
BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH) is characterized by steatosis
associated with liver inflammation. Steatosis causes recruitment of lymphocytes into the liver …

[HTML][HTML] A-subclass ATP-binding cassette proteins in brain lipid homeostasis and neurodegeneration

AP Piehler, M Özcürümez, WE Kaminski - Frontiers in psychiatry, 2012 - frontiersin.org
The A-subclass of ATP-binding cassette (ABC) transporters comprises 12 structurally related
members of the evolutionarily highly conserved superfamily of ABC transporters. ABCA …

[HTML][HTML] Genome-wide association between single nucleotide polymorphisms with beef fatty acid profile in Nellore cattle using the single step procedure

MVA Lemos, HLJ Chiaia, MP Berton, FLB Feitosa… - BMC genomics, 2016 - Springer
Background Saturated fatty acids can be detrimental to human health and have received
considerable attention in recent years. Several studies using taurine breeds showed the …

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

M Hoekstra, Z Li, JK Kruijt, M Van Eck… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Recent studies have suggested that variations in PNPLA3 are
associated with non-alcoholic fatty liver disease (NAFLD). To gain insight into the potential …

Nonalcoholic fatty liver disease is associated with an altered hepatocyte microRNA profile in LDL receptor knockout mice

M Hoekstra, RJ van der Sluis, J Kuiper… - The Journal of nutritional …, 2012 - Elsevier
MicroRNAs modulate processes associated with cell cycle control and differentiation. Here
we explored the potential of microRNAs in the modulation of hepatic lipid metabolism and …

[HTML][HTML] Management of hypercholesterolemia through dietary ß-glucans–insights from a zebrafish model

AH Gora, S Rehman, V Kiron, J Dias… - Frontiers in …, 2022 - frontiersin.org
Consumption of lipid-rich foods can increase the blood cholesterol content. β-glucans have
hypocholesterolemic effect. However, subtle changes in their molecular branching can …

Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice

D Ye, I Meurs, M Ohigashi, L Calpe-Berdiel… - Biochemical and …, 2010 - Elsevier
OBJECTIVES: To determine the role of macrophage ATP-binding cassette transporter A5
(ABCA5) in cellular cholesterol homeostasis and atherosclerotic lesion development …

ATP-binding cassette transporter A subfamily 8 is a sinusoidal efflux transporter for cholesterol and taurocholate in mouse and human liver

K Sasaki, M Tachikawa, Y Uchida, S Hirano… - Molecular …, 2018 - ACS Publications
The ATP-binding cassette (ABC) transporter A subfamily 8 (ABCA8) belongs to the ABCA6-
like transporters subgroup, which is distinct from the ABCA1-like subgroup in the ABCA …

Differential expression and functionality of ATP‐binding cassette transporters in the human hair follicle

IS Haslam, C El‐Chami, H Faruqi… - British Journal of …, 2015 - academic.oup.com
Background ATP‐binding cassette (ABC) transporters are involved in the active transport of
an extremely diverse range of substrates across biological membranes. These transporters …