Variation is important: warranting chromatin function and dynamics by histone variants

D Jiang, F Berger - Current Opinion in Plant Biology, 2023 - Elsevier
The chromatin of flowering plants exhibits a wide range of sequence variants of the core and
linker histones. Recent studies have demonstrated that specific histone variant enrichment …

[HTML][HTML] Histone variants take center stage in shaping the epigenome

M Borg, D Jiang, F Berger - Current Opinion in Plant Biology, 2021 - Elsevier
Highlights•The combination of histone variants greatly expands nucleosome diversity.•H2A
and H2B variants occupy distinct chromatin landscapes.•Histone H3. 1 controls epigenetic …

Structure and mechanism of histone methylation dynamics in Arabidopsis

H Hu, J Du - Current opinion in plant biology, 2022 - Elsevier
Histone methylation plays a central role in regulating chromatin state and gene expression
in Arabidopsis and is involved in a variety of physiological and developmental processes …

Histone tales: lysine methylation, a protagonist in Arabidopsis development

K Cheng, Y Xu, C Yang, L Ouellette… - Journal of …, 2020 - academic.oup.com
Histone methylation plays a fundamental role in the epigenetic regulation of gene
expression driven by developmental and environmental cues in plants, including …

DNA polymerase epsilon binds histone H3. 1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation

C Wang, J Huang, Y Li, J Zhang, C He… - Proceedings of the …, 2022 - National Acad Sciences
Heterochromatin is essential for genomic integrity and stability in eukaryotes. The
mechanisms that regulate meiotic heterochromatin formation remain largely undefined …

H3. 1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation

J Dong, C LeBlanc, A Poulet, B Mermaz… - The Plant …, 2021 - academic.oup.com
Epigenetic mechanisms play diverse roles in the regulation of genome stability in
eukaryotes. In Arabidopsis thaliana, genome stability is maintained during DNA replication …

The role of ATXR6 expression in modulating genome stability and transposable element repression in Arabidopsis

ME Potok, Z Zhong, CL Picard, Q Liu… - Proceedings of the …, 2022 - National Acad Sciences
ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) AND ATXR6 are required for
the deposition of H3K27me1 and for maintaining genomic stability in Arabidopsis. Reduction …

[HTML][HTML] TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis

L Wang, M Xue, H Zhang, L Ma, D Jiang - Cell Reports, 2023 - cell.com
The stability of eukaryotic genomes relies on the faithful transmission of DNA sequences
and the maintenance of chromatin states through DNA replication. Plant TONSOKU (TSK) …

PCNA inhibition enhances the cytotoxicity of β-lapachone in NQO1-Positive cancer cells by augmentation of oxidative stress-induced DNA damage

X Su, J Wang, L Jiang, Y Chen, T Lu, MS Mendonca… - Cancer letters, 2021 - Elsevier
Abstract β-Lapachone is a classic quinone-containing antitumor NQO1-bioactivatable drug
that directly kills NQO1-overexpressing cancer cells. However, the clinical applications of β …

AtMCM10 promotes DNA replication‐coupled nucleosome assembly in Arabidopsis

X Zhao, J Wang, D Jin, J Cheng, H Chen… - Journal of Integrative …, 2023 - Wiley Online Library
ABSTRACT Minichromosome Maintenance protein 10 (MCM10) is essential for DNA
replication initiation and DNA elongation in yeasts and animals. Although the functions of …