Metallic implants sometimes fail in orthopedic surgeries due to insufficient bio-functionality,
implant-associated infections, poor osteointegration due to high inertness (Ti, Co–Cr …

High-performance bioceramics are required for preventing failure and prolonging the life-
time of bone grafting scaffolds and osseous implants. The proper identification and …

Among biomedical community, great efforts have been realized to develop antibacterial
coatings that avoid implant-associated infections. To date, conventional mono-functional …

Plasma sprayed coatings composed of stoichiometric hydroxyapatite have been extensively
used to improve integration of metallic implants in the host bone, as hydroxyapatite (HA) is …

Today, the treatment of implant-associated infections with conventional mono-functional
antibacterial coatings has not been effective enough for a prosperous long-term …

Tissue engineering and regenerative medicine utilize mesenchymal stem cells (MSCs) and
their secretome in efforts to create or induce functional tissue replacement. Exosomes are …

Orthopedic infections pose severe societal and economic burden and interfere with the
capability of the implanted devices to integrate in the host bone, thus significantly increasing …

Human dental pulp is considered an interesting source of adult stem cells, due to the low-
invasive isolation procedures, high content of stem cells and its peculiar embryological …

Reconstruction of gradient organic/inorganic tissues is a challenging task in orthopaedics.
Indeed, to mimic tissue characteristics and stimulate bone regeneration at the interface, it is …

Objectives To evaluate the regenerative potential of human dental pulp stem cells (hDPSCs)
in an animal model of stress urinary incontinence (SUI). SUI, an involuntary leakage of urine …