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The aim of this review was to consider the effects of induced hypocapnia both on systemic
physiology and on the physiology of the intracranial system. Hyperventilation lowers …

Infections are a leading cause of death in stroke patients. In a mouse model of focal cerebral
ischemia, we tested the hypothesis that a stroke-induced immunodeficiency increases the …

Background and Purpose—Pneumonia has been estimated to occur in about one third of
patients after acute stroke. Only limited data are available on stroke-associated pneumonia …

We hypothesized that variation in extubating brain injured patients would affect the
incidence of nosocomial pneumonia, length of stay, and hospital charges. In a prospective …

The mechanism of immunodepression after brain injury is not yet clear. Here we
demonstrate rapid systemic release of the immunoinhibitory cytokine interleukin-10 …

A respiratory therapist-driven weaning protocol incorporating daily screens, spontaneous
breathing trials (SBT), and prompts to caregivers has been associated with superior …

We prospectively evaluated the relation of upper airway, lower airway, and gastric
colonization patterns with the development of pneumonia and its etiology in 48 patients with …

In comatose patients admitted to an ICU, particularly those with head injury, the incidence of
early onset pneumonia is exceedingly high. We performed an open, prospective …

Mortality rate attributable to ventilator-associated nosocom... : Critical Care Medicine
Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult …